Oxyquinoline sulfate is a polymer.
定义
Oxyquinoline sulfate is a polymer.
来源: PubChem
美国FDA 物质登记 · UNII 61VUG75Y3P · 登记名称 OXYQUINOLINE SULFATE · 单一化学物质
Oxyquinoline Sulfate is the salt of oxyquinoline and sulfuric acid. It conforms to the formula:
化妆品中的作用
安全与法规参考
- 限用·禁用
- 阿根廷 · 巴西 · 韩国 · 欧盟 · 台湾 · 中国
- 限用
- 欧盟 · 英国
来源: 韩国食药处 化妆品法规信息 · 欧盟化妆品法规 · 英国化妆品法规
东盟
- Field of application and/or use : (a) Stabilizer for hydrogen peroxide in rinse-off hair care preparations. (b) Stabilizer for hydrogen peroxide in non-rinse-off hair-care preparations.
- Maximum authorised concentration in the finished cosmetic product : (a) 0.3% calculated as base (b) 0.03% calculated as base
加拿大
- Conditions of Use by product type : (a) As stabilizers for hydrogen peroxide in rinse-off hair products (b) As stabilizers for hydrogen peroxide in leave-on hair products
- Maximum Concentration Permitted : (a) 0.3% (b) 0.03%
来源: 韩国食药处 化妆品法规信息
未列入韩国有毒物质 GHS 分类 · 现有化学物质
欧盟化妆品法规 附录III(限用物质) 第51项 · 最高浓度 (a) (0,3 % as base) (b) (0,03 % as base) · 适用 (a) Stabilizer for hydrogen peroxide in rinse-off hair products (b) Stabilizer for hydrogen peroxide in leave-on hair products
来源: 欧盟限用成分(附录III)
Restriction II/395 III/51
来源: 欧盟 CosIng 成分清单
Reviewed by CIR: Final Amended Report on the Safety of Oxyquinoline and Oxyquinoline Sulfate as used in Cosmetics
来源: 美国CIR 安全性评估
Reviewed by CIR: Final Report on the Safety Assessment of Oxyquinoline and Oxyquinoline Sulfate
来源: 美国CIR 安全性评估
CIR reviewed this ingredient and flagged its status as: Insufficient Data Announcement: Amended Safety Assessment of Oxyquinoline and Oxyquinoline Sulfate as Used in Cosmetics (insufficient data or use not supported — CIR's own classification, not a full safety-as-used conclusion).
来源: 美国CIR 安全性评估
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 134-31-6
- EC No.欧盟化学品目录编号
- 205-137-1
- DTXSID美国EPA化学品编号
- DTXSID6025436
- DTXCID美国EPA化合物编号
- DTXCID605436
- IUPAC
- Sulfuric acid--quinolin-8-ol (1/2)
- 分子式
- C18H16N2O6S
- 分子量
- 388.39 g/mol
实测物性
- 性状
- 8-hydroxyquinoline sulfate is a pale yellow to yellow crystalline powder with a slight saffron odor. Burning taste. (NTP, 1992) · Light yellow solid with mild odor of saffron, [Merck Index] Yellow crystalline solid, [Sigma-Aldrich MSDS]
- 沸点
- 267 °C @760 [mm Hg]
- 熔点
- 333 to 360 °F (NTP, 1992)
- 溶解性
- greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)
- 密度
- 1.034 @ 20°C
- pH
- 2.7 (at 20 °C)
- 熔点/凝固点
- 183.74 ℃
- 初沸点和沸程
- 267 ℃(at 760 mmHg)
- 闪点
- 143.1 ℃
- 蒸气压
- (8.34E-14 mmHg at 25 °C)
- 溶解度
- 1000 g/ℓ(at 20 °C)
- 蒸气密度
- 1.26 (g/cm3)
- 正辛醇/水分配系数(Kow)
- 4.30880
- 分子量
- 388.394
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 6 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Biocide3
- Emulsifier2
- Chelating agent1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 1 项、眼部试验 0 项。
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 1 项试验
- Category 6.3B (Category 3)
Skin Irritation · Read Across
来源: 美国EPA CompTox
相关文献
- Final Report on the Safety Assessment of Oxyquinoline and Oxyquinoline Sulfate · 1992
- Final Amended Report on the Safety Assessment of Oxyquinoline and Oxyquinoline Sulfate as Used in Cosmetics1 · 2006
- Skin Infections Respond to Hydrocortisone + Oxyquinoline Sulfate · 1987
- [Study of a drug combination with contraceptive, antibacterial, antimycotic and prophylactic action, for topical use in venereal diseases. 4. Effect of the combination of oxyquinoline sulfate, copper sulfate and lactic acid on Trichomonas vaginalis and on Candida albicans in vivo]. · 1980
- [Study of a topical antibacterial, contraceptive, antifungal and anti-venereal pharmacological combination. III. Post-coital test of the spermicidal action of a combination of oxyquinoline sulfate, copper sulfate and lactic acid]. · 1979