P-CHLORO-M-CRESOL

p-Chloro-m-Cresol is the substituted phenol that conforms to the formula:

4-chloro-m-cresol is a hydroxytoluene that is 3-methylphenol which is substituted by a chlorine at position 4. A ryanodine receptor agonist. It has a role as an antimicrobial agent, a disinfectant and a ryanodine receptor agonist. It is a hydroxytoluene and a member of monochlorobenzenes.

来源: PubChem

美国FDA 物质登记 · UNII 36W53O7109 · 登记名称 CHLOROCRESOL · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

准用防腐剂

英国

来源: 东盟化妆品指令 · 欧盟化妆品法规 · 日本化妆品标准 · 台湾FDA 化妆品成分 · 英国化妆品法规

阿根廷 · 巴西

• Maximum concentration permitted at final product : 0.2%
• Other limitations and requirements : Prohibited in products intended to come into contact with mucous.

东盟

• Maximum authorised concentration in the finished cosmetic product : 0.2%
• Other limitations and requirements : Prohibited in products intended to come into contact with mucous membranes

加拿大

• Conditions of Use by product type : (a) Not permitted in cosmetics intended to be used on or around mucosal membranes such as eyes, nose or mouth (b) Other cosmetics
• Maximum Concentration Permitted : (b) 0.1%
• Warnings and Cautionary Statements: (to the effect of) : "Do not use in the area of the eye, mouth or nose"

台湾

• 倘前述三國家地區政府管理有差異時，則採其中限量規定方式最安全者。
• ※ 本表所稱之口腔製劑，包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
• 用途 : 防腐
• 最大配合量 : 0.2% (不得使用於接觸黏膜部位產品)
• 0.2%

日本

• 每100g最大配合量(Maximum amount of ingredient per 100 g) : 0.50(0.50 g)

中国

• 最大配合量 : 0.2%

韩国

• 最大配合量 : 0.04%

欧盟

• Product Type, body parts : Not to be used in products applied on mucous membranes
• Maximum concentration in ready for use preparation : 0.2%

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息（环境公团）

欧盟化妆品法规 附录V（准用防腐剂） 第24项 · 最高浓度 0.2% · 适用 Not to be used in products applied on mucous membranes

来源: 欧盟准用防腐剂（附录V）

Restriction V/24 · Other restriction: ban substances that deplete the ozone layer

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Final Report on the Safety Assessment of Sodium p-Chloro-m-Cresol, p-Chloro-m-Cresol, Chlorothymol, Mixed Cresols, m-Cresol, o-Cresol, p-Cresol, Isopropyl Cresols, Thymol, o-Cymen-5-ol and Carvacrol

来源: 美国CIR 安全性评估

Reviewed by CIR: Final Report on the Safety Assessment of p-Chloro-m-Cresol

来源: 美国CIR 安全性评估