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Ingredients

Ingredient Dictionary

P-METHYLAMINOPHENOL

4-methylaminophenol is the phenol that is the N-methyl derivative of 4-aminophenol.

Korean limit
0.68%
Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 0 list it before the 1% line and 1 after it (usually 1% or less).

Products using this ingredient

1 of 1 confirmed · likeliest to carry enough first

Definition

4-methylaminophenol is the phenol that is the N-methyl derivative of 4-aminophenol. It has a role as an allergen. It is functionally related to a 4-aminophenol.

Source: PubChem

US FDA substance register · UNII 11W1883EFB · registered name P-METHYLAMINOPHENOL · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Dyes hairHAIR DYEING

Safety & regulatory references

Restricted
South Korea · Taiwan · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS)

ASEAN

  • Field of application and/or use : Hair dye substance in oxidative hair dye products. Use for dyeing eyelashes and eyebrows is not permitted.
  • Other limitations and requirements : After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.68 % (as sulphate) • Do not use with nitrosating systems • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers The direction for use “wear suitable gloves” must be included in label or leaflet text.
  • Conditions of use and warning which must be printed on the labels : The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows

China

  • Maximum concentration : 0.68%

European Union

  • Product Type, body parts : Hair dye in oxidative hair dye products
  • Other : Afther mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,68% (as sulphate) - Do not use with nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers
  • Wording of conditions of use and warnings : Hair colourants can cause severe allergic reactions

Source: MFDS (Korea) cosmetic regulatory information

Restriction III/223

Source: EU CosIng ingredient list

Restriction III/223 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Final Amended Report on the Safety Assessment of p-Methylaminophenol Sulfate and p-Methylaminophenol

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of p-Methylaminophenol Sulfate

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Insufficient Data Announcement: Safety Assessment of p-Methylaminophenol andp-Methylaminophenol Sulfate as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

CIR reviewed this ingredient and flagged its status as: Insufficient Data Announcement: Safety Assessment of p-Methylaminophenol andp-Methylaminophenol Sulfate as Used in Cosmetics (insufficient data or use not supported — CIR's own classification, not a full safety-as-used conclusion).

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Names & identifiers

P-METHYLAMINOPHENOLINCIp-메칠아미노페놀Korean label name (MFDS standard)p-메칠아미노페놀설페이트Korean label name (MFDS standard)Phenol, 4-(methylamino)-SynonymP-METHYLAMINOPHENOL SULFATESynonym
CAS No.chemical registry number
150-75-4
EC No.EU chemical inventory number
205-768-2
DTXSIDUS EPA chemical ID
DTXSID8043783
DTXCIDUS EPA compound ID
DTXCID6023783
IUPAC
4-(Methylamino)phenol
Molecular formula
C7H9NO
Molecular weight
123.155 g/mol

Measured properties

Appearance
solid
Melting/freezing point
87
Initial boiling point and range
209~211 ℃ (1.6 kPa)
Vapour pressure
0.00307 ㎜Hg ((25℃))
Water solubility
1.17 g/100㎖ ((25℃))
n-Octanol/water partition coefficient (Kow)
0.79
Molecular weight
123.15

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Dye2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 0 eye studies are on record.

Classed as moderate2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies
  • SkinSens1
    Skin Sensitization · QSAR Predicted
  • SkinIrr2
    Skin Irritation · QSAR Predicted

Source: US EPA CompTox dashboard

Related literature

Linked databases 24