Palmatine is a berberine alkaloid and an organic heterotetracyclic compound.
Definition
US FDA substance register · UNII G50C034217 · registered name PALMATINE · single chemical substance
Palmatine is a berberine alkaloid and an organic heterotetracyclic compound. It has a role as a plant metabolite.
Source: PubChem
Cosmetic roles
Slows spoilage by oxygenANTIOXIDANT
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name パルマチン: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
PALMATINEINCI팔마틴Korean label name (MFDS standard)パルマチンJapanese labelling name
- CAS No.chemical registry number
- 3486-67-7
- DTXSIDUS EPA chemical ID
- DTXSID9048065
- DTXCIDUS EPA compound ID
- DTXCID0028036
- IUPAC
- 2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[3,2-a]isoquinolin-7-ium
- Molecular formula
- C21H22NO4
- Molecular weight
- 352.409 g/mol
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Antioxidant4
Source: US EPA CompTox dashboard
Related literature
- The encapsulation mechanism of palmatine in anionic liposomes during flash nanoprecipitation. · 2025
- Botanical Sources, Pharmacokinetics, and Therapeutic Efficacy of Palmatine and Its Derivatives in the Management of Cancer: A Comprehensive Mechanistic Analysis · 2024
- Antifungal activity of berberine hydrochloride and palmatine hydrochloride against Microsporum canis -induced dermatitis in rabbits and underlying mechanism · 2015
- Assessment of DNA damage and cytotoxicity of palmatine on human skin epithelial carcinoma cells · 2014
- In vitro inhibitory effects of palmatine from Enantia chlorantha on Trypanosoma cruzi and Leishmania infantum · 2009
Linked databases 15
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese