1-Hexadecylamine is an alkylamine.
Definition
1-Hexadecylamine is an alkylamine.
Source: PubChem
US FDA substance register · UNII O2H0Q02M4P · registered name Hexadecylamine · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted or banned
- China · South Korea
Source: MFDS (Korea) cosmetic regulatory information
Argentina · Brazil
- Maximum concentration permitted at final product : Under maximum secondary amine: 0.5%
- Other limitations and requirements : No use with nitrosating systems. Minimum 99% -Pureza. Maximum -Tenor of secondary amines in raw materials 0.5%. Maximum nitrosamine -Tenor: 50 ug / kg. -Envasar / Nitrite - free store in containers.
ASEAN
- Maximum authorised concentration in the finished cosmetic product : Maximum secondary amine content: 0.5%
- Other limitations and requirements : • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content: 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers
European Union
- Maximum concentration in ready for use preparation : Maximum secondary amine content: 0.5%
- Other : - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction III/61 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 143-27-1
- EC No.EU chemical inventory number
- 205-596-8
- DTXSIDUS EPA chemical ID
- DTXSID7025390
- DTXCIDUS EPA compound ID
- DTXCID805390
- IUPAC
- Hexadecan-1-amine
- Molecular formula
- C16H35N
- Molecular weight
- 241.463 g/mol
Measured properties
- Appearance
- solid
- Melting/freezing point
- 46.8 ℃
- Initial boiling point and range
- 322.5 ℃
- Water solubility
- 0.482 ㎎/ℓ (@ 25 ℃, est.)
- Vapour density
- 8.33
- n-Octanol/water partition coefficient (Kow)
- 6.37 ()
- Molecular weight
- 241.46
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Anti-static agent1
- Lubricating agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- SkinIrr2
Skin Irritation · QSAR Predicted - Category 8.2C (Category 1C)
Skin Irritation · Read Across - SkinSens1
Skin Sensitization · QSAR Predicted - Category 8.3A (Category 1)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata