Pantethine is an organic disulfide that consists of two molecules of pantothenic acid linked by amide bonds to a cysteamine disulfide bridging group.
How much products actually contain
No product states its amount yet.
Of the products containing it, 13 list it before the 1% line and 0 after it (usually 1% or less).
Products using this ingredient
12 of 13 confirmed · likeliest to carry enough first · See all 13
OLAPLEXOLAPLEX Lashbond® Building Serum
M·A·CM·A·C Extended Play Gigablack Lash Mascara - Intense Black
M·A·CM·A·C M·A·CStack Legit Lift Lash Primer - Stark Stack
OLAPLEXOLAPLEX Browbond® Building Serum
M·A·CM·A·C M·A·CStack Waterproof Mascara - Black Stack
M·A·CM·A·C M·A·CStack Mascara - Chestnut Stack
M·A·CM·A·C M·A·CStack Mascara - M·A·CStack Micro Mascara
M·A·CM·A·C M·A·CStack Mascara - Stack Black
M·A·CM·A·C M·A·CStack Mascara / Mini M·A·C - Black Stack
M·A·CM·A·C M·A·CStack MICRO Mascara / Mini M·A·C - Black Stack
M·A·CM·A·C In Extreme Dimension 3D Black Lash Mascara - 3D Black
M·A·CM·A·C In Extreme Dimension Lash Mascara / Mini M·A·C - 3D Black
Definition
Pantethine is an organic disulfide that consists of two molecules of pantothenic acid linked by amide bonds to a cysteamine disulfide bridging group. It has a role as a coenzyme and a nutraceutical. It is functionally related to a pantothenic acid.
Source: PubChem
US FDA substance register · UNII 7K81IL792L · registered name PANTETHINE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name パンテチン: 本品は、次の化学式で表されるジスルフィド化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 138148-35-3
- CAS No.chemical registry number
- 16816-67-4
- EC No.EU chemical inventory number
- 240-842-8
- DTXSIDUS EPA chemical ID
- DTXSID9046815
- DTXCIDUS EPA compound ID
- DTXCID901473899
- IUPAC
- (2R,2'R)-N,N'-{Disulfanediylbis[ethane-2,1-diylazanediyl(3-oxopropane-3,1-diyl)]}bis(2,4-dihydroxy-3,3-dimethylbutanamide) (non-preferred name)
- Molecular formula
- C22H42N4O8S2
- Molecular weight
- 554.72 g/mol
Measured properties
- Appearance
- Solid
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner5
Source: US EPA CompTox dashboard
Related literature
- Natural therapies for ocular disorders, part two: cataracts and glaucoma. · 2001
- THE PATHENINE/VANINE PATHWAY CONTROLS ROS-INDUCED SKIN FIBROSIS · 2016
- Imbalance of the Vanin-1 Pathway in Systemic Sclerosis · 2016
- Topical Apolipoprotein A-1 May Have a Beneficial Effect on the Corneal Epithelium in a Mouse Model of Dry Eye: A Pilot Study · 2008
- Effect of pantethine on the biosynthesis of cholesterol in human skin fibroblasts. · 1982
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English