How much products actually contain
15 products state the amountmedian 0.2%
- under 0.01% 1
- 0.01–0.1% 3
- 0.1–1% 10
- 1% or more 1
Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.
Of the products containing it, 73 list it before the 1% line and 60 after it (usually 1% or less).
Products using this ingredient
12 of 132 confirmed · likeliest to carry enough first · See all 132
The Yeobaek26Cloud Azulene Enzyme Peeling Powder Pack1.5% stated
ISOVGLACIAL ENZYME POWDER WASH0.7% stated
CellFusionCCellFusionC PHA Enzyme Granule Peels Powder0.45% stated
WISELYEnzyme Rice Powder Cleanser0.2% stated
ElizaveccaElizavecca Hell-Pore Clean Up Enzyme Powder Wash0.2% stated
AriulThe Perfect Yulmu Enzyme Powder Cleanser0.2% stated
AriulAriul The Perfect Yulmu Enzyme Scrub Powder Cleanser0.2% stated
Papa RecipeBlemish Enzyme Powder Cleanser 130g Jumbo Set0.19% stated
MEDIHEALPhyto-enzyme Peeling Toner Pad 100 Sheets0.02% stated
MEDIHEALPhyto-enzyme Peeling Toner Pad 14 Sheets0.02% stated
Grown AlchemistGrown Alchemist Enzyme Exfoliator - 20ml
Grown AlchemistGrown Alchemist Enzyme Exfoliator - 75ml
Definition
US FDA substance register · UNII A236A06Y32 · registered name Papain · protein
Papain
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name パパイン: 本品は、パパイア Carica papaya の未熟な果実や葉から得られる乳汁中に存在するたん白分解酵素である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 9001-73-4
- EC No.EU chemical inventory number
- 232-627-2
- DTXSIDUS EPA chemical ID
- DTXSID7044184
Measured properties
- Appearance
- solid
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 16 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner6
- Chemical reaction regulator4
- Processing aids not otherwise specified2
- Anti-static agent2
- Surface modifier1
- Thickening agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Skin Irrit. 2
Skin Irritation · Authoritative - Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Eye Irrit. 2
Eye Irritation · Authoritative
Source: US EPA CompTox dashboard
Related literature
- Liposomes and transferosomes in the delivery of papain for the treatment of keloids and hypertrophic scars · 2023
- Semi-Solid Pharmaceutical Formulations for the Delivery of Papain Nanoparticles · 2020
- Papain Activity in Dextran Solution for Keratin Hydrolysis · 2014
- Papain‐induced allergic reactions · 1978
Linked databases 14
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- Tlooto literature search 2 3 4
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata