1,7-dimethylxanthine is a dimethylxanthine having the two methyl groups located at positions 1 and 7.
Definition
1,7-dimethylxanthine is a dimethylxanthine having the two methyl groups located at positions 1 and 7. It is a metabolite of caffeine and theobromine in animals. It has a role as a central nervous system stimulant, a mouse metabolite, a human xenobiotic metabolite and a human blood serum metabolite.
Source: PubChem
US FDA substance register · UNII Q3565Y41V7 · registered name PARAXANTHINE · single chemical substance
Paraxanthine is the heterocyclic compound.
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name パラキサンチン: 本品は、次の化学式で表される複素環式化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 611-59-6
- EC No.EU chemical inventory number
- 210-271-9
- DTXSIDUS EPA chemical ID
- DTXSID2052281
- DTXCIDUS EPA compound ID
- DTXCID2030853
- IUPAC
- 1,7-Dimethyl-3,7-dihydro-1H-purine-2,6-dione
- Molecular formula
- C7H8N4O2
- Molecular weight
- 180.167 g/mol
Measured properties
- Appearance
- Faint yellow fine crystals, [MSDSonline] · Solid
- Melting point
- 351 - 352 °C
- Solubility
- >27 [ug/mL] (The mean of the results at pH 7.4)
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Related literature
- Plasma proteometabolome in lung cancer: exploring biomarkers through bidirectional Mendelian randomization and colocalization analysis. · 2024
- Effects of endocrine disrupting chemicals, blood metabolome, and epigenetics on breast cancer risk: A multi-dimensional mendelian randomization study. · 2025
- Alterations of gut microbiota and gut metabolites in the young‐adult vitiligo patients · 2023
- Article title: Transcriptional profiling efficacy to define biological activity similarity for cosmetic ingredients’ safety assessment based on next-generation read-across · 2022
- New Framework for a Non-Animal Approach Adequately Assures the Safety of Cosmetic Ingredients - A Case Study on Caffeine. · 2021
Linked databases 15
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese