Nonanoic acid is a C9 straight-chain saturated fatty acid which occurs naturally as esters of the oil of pelargonium.
定義
Nonanoic acid is a C9 straight-chain saturated fatty acid which occurs naturally as esters of the oil of pelargonium. Has antifungal properties, and is also used as a herbicide as well as in the preparation of plasticisers and lacquers. It has a role as an antifeedant, a plant metabolite, a Daphnia magna metabolite and an algal metabolite. It is a straight-chain saturated fatty acid and a medium-chain fatty acid. It is a conjugate acid of a nonanoate. It derives from a hydride of a nonane.
出典: PubChem
米国FDA 物質登録 · UNII 97SEH7577T · 登録名 PELARGONIC ACID · 単一の化学物質
化粧品での役割
安全性・規制情報
韓国の有害物質GHS分類なし · 既存化学物質
Reviewed by CIR: Final report of the Cosmetic Ingredient Review Expert Panel on the safety assessment of Pelargonic Acid (nonanoic acid) and nonanoate esters
出典: 米国CIR 安全性評価
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
- CAS No.化学物質登録番号
- 112-05-0
- EC No.EU化学物質目録番号
- 203-931-2
- DTXSID米国EPA化学物質番号
- DTXSID3021641
- DTXCID米国EPA化合物番号
- DTXCID901641
- IUPAC
- Nonanoic acid
- 分子式
- C9H18O2
- 分子量
- 158.241 g/mol
測定された物性
- 性状
- Liquid, Large Crystals · Colorless or yellowish liquid, mp = 12.5 deg C, [Hawley]
- 臭い
- FATTY ODOR · COCONUT AROMA
- 沸点
- 254.5 °C · Boiling point = 255.6 °C
- 融点
- 12.4 °C · 12.3 °C
- 溶解性
- Soluble in ethanol, chloroform, ether · 1:8 IN 50% ALCOHOL, 1:3 IN 60% ALCOHOL, INSOL IN WATER, SOL IN MOST ORG SOLVENTS
- 密度
- 0.9052 g/cu cm at 20 °C · 0.901-0.906
- 粘度
- 8.08 mPa.sec at 20 °C · 7.00 cP (25℃)
- 解離定数
- pKa = 4.95 at 25 °C
- 色
- 無色
- 臭いの閾値
- 3 ppm (3~9)
- 融点・凝固点
- 12 ℃(ca.)
- 初留点および沸点範囲
- 249~271 ℃ (1013.25 hPa)
- 引火点
- 133 ℃(ca.)
- 蒸気圧
- (ca. 0.22hPa at 50℃)
- 溶解度
- (ca. 0.03 vol% 25℃)
- 蒸気密度
- 5.45
- 比重
- 0.904 (20℃)
- n-オクタノール/水分配係数（Kow）
- 2.84 (ca.)
- 自然発火温度
- 405 ℃
- 分子量
- 158.27
物質そのものを測定した値です。安全保健公団（KOSHA）の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。
出典: PubChem · 韓国安全保健公団 SDS
製品が実際に使っている用途
米国EPAにこの成分を届け出た製品16件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。
- Flavouring and nutrient2
- No specific technical function2
- Fragrance2
- Biocide2
- Soil amendments2
- Emulsifier1
- Cleaning agent1
- Monomers1
その他の用途 3件
- Deodorizer1
- Intermediate1
- Lubricating agent1
出典: 米国EPA CompTox
刺激・感作試験の記録
皮膚試験9件・眼試験4件の記録があります。
試験の結論はおおむね一致しています（100%）。 原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。
試験13件をすべて見る
- Skin Irrit. 2
Skin Irritation · Authoritative - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Skin corrosion/irritation - Category 2
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Severe Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Ambiguous
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Category 2
Skin Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Eye Irrit. 2
Eye Irritation · Authoritative - Serious eye damage/eye irritation - Category 2
Eye Irritation · Screening - Category 2A
Eye Irritation · Screening
出典: 米国EPA CompTox
関連文献
- Mixtures of Diethyl Azelate as Novel Nonopioid Modalities for Pain Management · 2025
- Postharvest Reduction of Salmonella enterica on Tomatoes Using a Pelargonic Acid Emulsion · 2021
- Mechanism of PAVA-induced toxicity and inflammation in a cocultured skin cell model · 2025
- Thermal and Mechanical Characterisation of Poly(ω -Hydroxy Pelargonate): A Preliminary Study for Bioplastic · 2021
- Comparison of the Effects of Pelargonic Acid Vanillylamide and Capsaicin on Human Vanilloid Receptors · 2013