What is this ingredient?

미국 FDA 물질 등록 · UNII OK17S3S98K · 등록명 PENTADECALACTONE · 단일 화학물질

All ingredients

Ingredient Dictionary

PENTADECALACTONE

Cyclopentadecanolide is a macrolide.

How much products actually contain

No product states its amount yet.

Of the products containing it, 3 list it before the 1% line and 16 after it (usually 1% or less).

Products using this ingredient

12 of 19 confirmed · likeliest to carry enough first · See all 19

Definition

US FDA substance register · UNII OK17S3S98K · registered name PENTADECALACTONE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cyclopentadecanolide is a macrolide.

Source: PubChem

Pentadecalactone is the lactone of 15-hydroxypentadecanoic acid that conforms to the formula

Cosmetic roles

Gives the product a scentPERFUMINGListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE

Safety & regulatory references

Restricted: International fragrance standard (IFRA)

Source: IFRA fragrance standards

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ペンタデカラクトン: 本品は、15－ヒドロキシペンタデカン酸のラクトンであり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

PENTADECALACTONEINCI펜타데카락톤Korean label name (MFDS standard)Oxacyclohexadecan-2-oneSynonymペンタデカラクトンJapanese labelling name

CAS No.chemical registry number: 106-02-5
EC No.EU chemical inventory number: 203-354-6
DTXSIDUS EPA chemical ID: DTXSID6044359
DTXCIDUS EPA compound ID: DTXCID4024359

IUPAC: 1-Oxacyclohexadecan-2-one
Molecular formula: C15H28O2
Molecular weight: 240.387 g/mol

Measured properties

Appearance: solid
Colour: white
Melting/freezing point: 32~38 ℃
Initial boiling point and range: 137 ℃(at 2㎜Hg)
Flash point: &amp, gt, 109 ℃
Water solubility: 0.06251 ㎎/ℓ
Relative density: 0.918
Molecular weight: 240.39

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 77 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance71
Deodorizer4
Flavouring and nutrient2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

6 skin studies and 1 eye studies are on record.

Classed as highly irritating4Classed as low6

The studies disagree (the most common conclusion covers 40%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 7 studies

High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
Classification not possible
Skin Sensitization · Screening
Classification not possible
Skin Irritation · Screening
Classification not possible
Eye Irritation · Screening