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Ingredients

Ingredient Dictionary

PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 621 list it before the 1% line and 1,003 after it (usually 1% or less).

Products using this ingredient

12 of 1,610 confirmed · likeliest to carry enough first · See all 1,610

Definition

US FDA substance register · UNII 255PIF62MS · registered name PENTAERYTHRITOL TETRAKIS(3-(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)PROPIONATE) · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate is the organic compound that conforms to the formula:

Cosmetic roles

Slows spoilage by oxygenANTIOXIDANT

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Safety Assessment of Pentaerythrityl Tetra-Di-t-Butyl Hydroxyhydrocinnamate as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name テトラ(ジ-t-ブチルヒドロキシヒドロケイヒ酸)ペンタエリスリチル: 本品は、次の化学式で表される芳香族化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATEINCIBenzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 2,2-bis[[3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1-oxopropoxy]methyl]-1,3-propanediyl esterSynonym펜타에리스리틸테트라-다이-t-부틸하이드록시하이드로신나메이트Korean label name (MFDS standard)テトラ(ジ-t-ブチルヒドロキシヒドロケイヒ酸)ペンタエリスリチルJapanese labelling name
CAS No.chemical registry number
6683-19-8
EC No.EU chemical inventory number
229-722-6
DTXSIDUS EPA chemical ID
DTXSID1027633
DTXCIDUS EPA compound ID
DTXCID007633
IUPAC
2,2-Bis({[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl]oxy}methyl)propane-1,3-diyl bis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate]
Molecular formula
C73H108O12
Molecular weight
1177.655 g/mol

Measured properties

Appearance
Dry Powder, Other Solid, Liquid, Large Crystals, CBI · White solid, [ICSC] White to off-white odorless powder or granules, [Addivant MSDS]
Melting point
110-125 °C · 230-257 °F
Solubility
Solubility in water: none
Density
1.15 g/cm³
Colour
white
Odour
odourless
Upper/lower flammability or explosive limits
- / - (1.37E-018mmHg(25℃))
Relative density
1.15
n-Octanol/water partition coefficient (Kow)
22.7 (25℃, calculated)
Decomposition temperature
116.5 ℃
Molecular weight
1177.70

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 161 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Antioxidant88
  • Stabilizing agent18
  • Processing aids not otherwise specified16
  • Fragrance13
  • Filler4
  • Pigment3
  • UV stabilizer3
  • Defoamer2
11 other uses
  • Reducing agent2
  • Intermediate2
  • pH regulating agent2
  • Heat stabilizer1
  • Preservative1
  • Catalyst1
  • Binder1
  • Lubricating agent1
  • Corrosion inhibitor1
  • Adhesion/cohesion promoter1
  • Surface modifier1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to

Source: US EPA CompTox dashboard

Related literature

Linked databases 20