Pentetic acid is a pentacarboxylic acid.
Definition
Pentetic acid is a pentacarboxylic acid. It has a role as a copper chelator. It is a conjugate acid of a pentetate(1-).
Source: PubChem
US FDA substance register · UNII 7A314HQM0I · registered name PENTETIC ACID · single chemical substance
Pentetic Acid is the substituted amine that conforms to the formula:
Cosmetic roles
Safety & regulatory references
- Banned
- ASEAN · European Union · 유럽
Source: EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1720
Reviewed by CIR: Final Report on the Safety Assessment of Sodium Pentetate and Pentetic Acid as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ペンテト酸: 本品は、次の化学式で表されるアミン誘導体である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 67-43-6
- EC No.EU chemical inventory number
- 200-652-8
- DTXSIDUS EPA chemical ID
- DTXSID2023434
- DTXCIDUS EPA compound ID
- DTXCID603434
- IUPAC
- N,N-Bis{2-[bis(carboxymethyl)amino]ethyl}glycine
- Molecular formula
- C14H23N3O10
- Molecular weight
- 393.349 g/mol
Measured properties
- Appearance
- CBI, Dry Powder · White to off-white solid, [Acros Organics MSDS]
- Boiling point
- Decomposes
- Melting point
- 219-220 ºC · 219 °C
- Solubility
- Highly soluble
- Dissociation constant
- pentabasic (1.5-10.6)
- Colour
- white
- Odour
- odourless
- Melting/freezing point
- 219 ℃
- Initial boiling point and range
- 106 ℃
- Flash point
- 200 ℃
- Water solubility
- 4800 ㎎/ℓ
- Decomposition temperature
- 219-230 ℃
- Molecular weight
- 393.35
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 106 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Cleaning agent64
- Chelating agent40
- Ion exchange agent2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - SkinIrr2
Skin Irritation · QSAR Predicted - Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
Linked databases 24
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese