What is this ingredient?

미국 FDA 물질 등록 · UNII 50C1307PZG · 등록명 PENTYLENE GLYCOL · 단일 화학물질

Are there usage precautions?

보습 효과,방부 대체제, 항균 효과 (추천 피부타입: 건성, 중성)

All ingredients

Ingredient Dictionary

PENTYLENE GLYCOL

How much products actually contain

No product states its amount yet.

Of the products containing it, 1,873 list it before the 1% line and 1,255 after it (usually 1% or less).

Products using this ingredient

12 of 3,084 confirmed · likeliest to carry enough first · See all 3,084

Definition

US FDA substance register · UNII 50C1307PZG · registered name PENTYLENE GLYCOL · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONINGBase that dissolves other ingredientsSOLVENT

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Safety Assessment of 1,2-Glycols as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ペンチレングリコール: 本品は、次の化学式で表される二価アルコールである。

Source: JCIA labelling names (Japan)

Names & identifiers

PENTYLENE GLYCOLINCI펜틸렌글라이콜Korean label name (MFDS standard)1,2-PentanediolSynonymペンチレングリコールJapanese labelling name

CAS No.chemical registry number: 5343-92-0
EC No.EU chemical inventory number: 226-285-3
DTXSIDUS EPA chemical ID: DTXSID10863522
DTXCIDUS EPA compound ID: DTXCID80812123

IUPAC: Pentane-1,2-diol
Molecular formula: C5H12O2
Molecular weight: 104.149 g/mol

Measured properties

Appearance: Liquid · Yellow hygroscopic liquid, [Acros Organics MSDS]
Colour: colourless
Odour: almost odourless
Melting/freezing point: -40 ℃
Initial boiling point and range: 209.4 ℃
Flash point: 110 ℃(c.c.)
Vapour pressure: 1.026 hPa (64.1℃)
Water solubility: 1000 g/ℓ (20℃)
Relative density: (0.98 g/㎤ (20℃))
n-Octanol/water partition coefficient (Kow): 0.06 (25℃)
Auto-ignition temperature: 380 ℃
Viscosity: (77.1 mPa s (20℃))
Molecular weight: 104.15

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 14 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Solvent6
Softener and conditioner5
Fragrance2
Photosensitive agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 2 eye studies are on record.

Classed as low3

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 5 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EPA OPP 81-5 (Acute Dermal Irritation) according to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) ; original guideline 406, adopted in 1981
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to
Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Severe Irritation
eye irritation: in vivo · Screening · EPA OPP 81-4 (Acute Eye Irritation) according to