Definition
US FDA substance register · UNII GID333S43J · registered name Pepsin · protein
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ペプシン: 本品は、胃粘膜から得られるタンパク分解酵素である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 9001-75-6
- EC No.EU chemical inventory number
- 232-629-3
- DTXSIDUS EPA chemical ID
- DTXSID701009848
Measured properties
- Appearance
- solid
- Water solubility
- 20 ㎎/ℓ
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner2
- Chemical reaction regulator1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Skin Irrit. 2
Skin Irritation · Authoritative - Eye Irrit. 2
Eye Irritation · Authoritative - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Predictive Value of Laryngeal Mucosa Pepsin in Therapeutic Response of Laryngopharyngeal Reflux. · 2022
- Extraction and characterization of pepsin-solubilized collagen from snakehead (Channa argus) skin: Effects of hydrogen peroxide pretreatments and pepsin hydrolysis strategies · 2019
- Analysis and improvement of stability of pepsin-solubilized collagen from skin of carp (Cyprinus carpio) · 2012
- Review article: effects of pepsin and alginate in an animal model of squamous cell carcinoma · 2011
- Extraction and characterisation of pepsin-solubilised collagens from the skin of bigeye snapper (Priacanthus tayenus and Priacanthus macracanthus). · 2010
Linked databases 13
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- Tlooto literature search 2 3 4 5
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata