Perfluorohexane is a fluoroalkane that is hexane in which all of the hydrogens have been replaced by fluorines.
Definition
Perfluorohexane is a fluoroalkane that is hexane in which all of the hydrogens have been replaced by fluorines. It has a role as a radioopaque medium and a non-polar solvent. It is a volatile organic compound, a fluoroalkane and a fluorocarbon. It derives from a hydride of a hexane.
Source: PubChem
US FDA substance register · UNII FX3WJ41CMX · registered name PERFLEXANE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name パーフルオロヘキサン: 本品は、次の化学式で表されるフッ素化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 355-42-0
- EC No.EU chemical inventory number
- 206-585-0
- DTXSIDUS EPA chemical ID
- DTXSID7046548
- DTXCIDUS EPA compound ID
- DTXCID5026548
- IUPAC
- Tetradecafluorohexane
- Molecular formula
- C6F14
- Molecular weight
- 338.044 g/mol
Measured properties
- Appearance
- liquid
- Colour
- colourless
- Melting/freezing point
- -4 ℃
- Initial boiling point and range
- 56 ℃
- Flash point
- 1 ℃
- Vapour pressure
- 232 ㎜Hg ((25 °C))
- Vapour density
- 11.7 ()
- Relative density
- 1.68 g/cm3 ((20 °C))
- n-Octanol/water partition coefficient (Kow)
- 5.65
- Viscosity
- 0.4 cSt ((25 °C))
- Molecular weight
- 338.0418
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent2
Source: US EPA CompTox dashboard
Related literature
- Ultrasound and fluorescence imaging of EGFR‑targeted nanodroplet binding kinetics · 2026
- Systemic and immunotoxicity induced by topical application of perfluorohexane sulfonic acid (PFHxS) in a murine model · 2024
- Systemic and immunotoxicity induced by topical application of perfluorohexane sulfonic acid (PFHxS) in a murine model (dataset). · 2024
- Plasma levels of per- and polyfluoroalkyl substances (PFAS) are associated with altered levels of proteins previously linked to inflammation, metabolism and cardiovascular disease. · 2023
- EGFR-Targeted Perfluorohexane Nanodroplets for Molecular Ultrasound Imaging · 2022
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese