Phenethyl isothiocyanate is an isothiocyanate having a phenethyl group attached to the nitrogen.
定义
Phenethyl isothiocyanate is an isothiocyanate having a phenethyl group attached to the nitrogen. It is a naturally occurring compound found in some cruciferous vegetables (e.g. watercress) and is known to possess anticancer properties. It has a role as a metabolite, an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor and an antineoplastic agent.
来源: PubChem
美国FDA 物质登记 · UNII 6U7TFK75KV · 登记名称 PHENETHYL ISOTHIOCYANATE · 单一化学物质
化妆品中的作用
为产品增添香味PERFUMING
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
PHENETHYL ISOTHIOCYANATEINCIBenzene, (2-isothiocyanatoethyl)-同义名
- CAS No.化学物质登记号
- 2257-09-2
- EC No.欧盟化学品目录编号
- 218-855-5
- DTXSID美国EPA化学品编号
- DTXSID5021120
- DTXCID美国EPA化合物编号
- DTXCID901120
- IUPAC
- (2-Isothiocyanatoethyl)benzene
- 分子式
- C9H9NS
- 分子量
- 163.24 g/mol
实测物性
- 性状
- Colorless to pale yellow liquid, [Merck Index] Clear colorless liquid, [Sigma-Aldrich MSDS] · Nearly Colourless liquid, Strong green irritating aroma
- 沸点
- 139.00 to 140.00 °C. @ 11.00 mm Hg · 139-140 °C
- 溶解性
- 110 mg/L @ 20 °C (exp) · Insoluble in water, Soluble in triacetin and heptane
- 密度
- 1.087-1.097
这是对物质本身测得的数值，并非原料商品的规格。
来源: PubChem
产品实际使用的用途
这是向美国 EPA 申报含该成分的 4 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Flavouring and nutrient2
- Fragrance2
来源: 美国EPA CompTox
相关文献
- Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling. · 2013
- Naturally-derived phenethyl isothiocyanate modulates apoptotic induction through regulation of the intrinsic cascade and resulting apoptosome formation in human malignant melanoma cells · 2024
- Phenethyl Isothiocyanate-Containing Carbomer Gel for Use against Squamous Cell Carcinoma · 2021
- Phenethyl isothiocyanate triggers apoptosis in human malignant melanoma A375.S2 cells through reactive oxygen species and the mitochondria-dependent pathways · 2014
- Antitumor activity of phenethyl isothiocyanate in HER2-positive breast cancer models · 2012