Ingredient Dictionary

PHENETHYL SALICYLATE

Phenethyl salicylate is a member of phenols and a benzoate ester.

Definition

Phenethyl salicylate is a member of phenols and a benzoate ester. It is functionally related to a salicylic acid.

Source: PubChem

US FDA substance register · UNII 6LDP0U8UB0 · registered name PHENETHYL SALICYLATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

PHENETHYL SALICYLATEINCIBenzoic acid, 2-hydroxy-, 2-phenylethyl esterSynonym

CAS No.chemical registry number: 87-22-9
EC No.EU chemical inventory number: 201-732-5
DTXSIDUS EPA chemical ID: DTXSID0052592
DTXCIDUS EPA compound ID: DTXCID7031165

IUPAC: 2-Phenylethyl 2-hydroxybenzoate
Molecular formula: C15H14O3
Molecular weight: 242.274 g/mol

Measured properties

Appearance: Solid · white granular crystals with a faint, balsamic, floral odour
Boiling point: 370.00 °C. @ 760.00 mm Hg · 190 °C (5 mm Hg)
Melting point: 44 °C
Solubility: insoluble in water, glycerol, glycols, soluble in organic solvents, oils · soluble (1 g in 20 ml of 95% ethanol) (in ethanol)
Colour: white
Melting/freezing point: 41 ℃
Initial boiling point and range: 345.09 ℃
Flash point: &amp, gt, 93.33 ℃
Flammability (solid, gas): not flammable
Vapour pressure: &amp, lt, 0.133 ㎩ (at 20°C)
Water solubility: 7.856 ㎎/ℓ
n-Octanol/water partition coefficient (Kow): 4.80 (Log Pow)
Molecular weight: 242.2726

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 13 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance11
Flavouring and nutrient2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

8 skin studies and 2 eye studies are on record.

Classed as highly irritating8Classed as moderate1Classed as low4

The study conclusions largely agree (62%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 10 studies

SkinIrr2
Skin Irritation · QSAR Predicted
Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: as mentioned below
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: as mentioned below
Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to
High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: as mentioned below
Severe Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to
High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to other guideline: as mentioned below
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to