Phenol red is 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups.
How much products actually contain
No product states its amount yet.
Of the products containing it, 0 list it before the 1% line and 1 after it (usually 1% or less).
Products using this ingredient
1 of 1 confirmed · likeliest to carry enough first
Definition
Phenol red is 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney. It has a role as a diagnostic agent, an acid-base indicator and a two-colour indicator. It is a member of phenols, a 2,1-benzoxathiole, a sultone and an arenesulfonate ester.
Source: PubChem
US FDA substance register · UNII I6G9Y0J1OJ · registered name Phenolsulfonphthalein · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name フェノールスルホンフタレイン: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 143-74-8
- EC No.EU chemical inventory number
- 205-609-7
- DTXSIDUS EPA chemical ID
- DTXSID8022408
- DTXCIDUS EPA compound ID
- DTXCID202408
- IUPAC
- 3,3-Bis(4-hydroxyphenyl)-2,1lambda~6~-benzoxathiole-1,1(3H)-dione
- Molecular formula
- C19H14O5S
- Molecular weight
- 354.38 g/mol
Measured properties
- Melting/freezing point
- &, gt, 300 ℃
- Water solubility
- (0.076%)
- Molecular weight
- 354.37
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- pH regulating agent1
Source: US EPA CompTox dashboard
Related literature
- Uric acid metabolism in psoriasis. · 1961
- The effect of wool fat and some of its constituents on the absorption of phenolsulfonphthalein through the intact skin. · 1952
- Enhancing effect of pyrrolidone derivatives on transdermal penetration of phenolsulfonphthalein and indomethacin from aqueous vehicle. · 1990
- Effect of systemic anaphylaxis on the absorption of salicylic acid from the rat small intestine. · 1984
- STUDIES ON THE TRANSFER OF ANTIGENIC INFORMATION FROM A GRAFT TO ITS HOST ENVIRONMENT IN THE HOMOGRAFT STATE · 1962
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese