Definition
US FDA substance register · UNII N95C96I48M · registered name 2-PROPENOIC ACID, 2-PHENOXYETHYL ESTER · single chemical substance
Phenoxyethyl Acrylate is the organic compound that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name アクリル酸フェノキシエチル: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 48145-04-6
- EC No.EU chemical inventory number
- 256-360-6
- DTXSIDUS EPA chemical ID
- DTXSID4040715
- DTXCIDUS EPA compound ID
- DTXCID2020715
- IUPAC
- 2-Phenoxyethyl prop-2-enoate
- Molecular formula
- C11H12O3
- Molecular weight
- 192.214 g/mol
Measured properties
- Appearance
- Liquid, CBI
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 23 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- UV stabilizer7
- Photosensitive agent3
- Chemical reaction regulator2
- Solvent2
- Intermediate2
- Viscosity modifier2
- Binder2
- Diluent2
1 other uses
- Processing aids not otherwise specified1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- SkinIrr2
Skin Irritation · QSAR Predicted - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) The Guinea pig maximization test - Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: Code of Federal Regulations, Title 16, Section 1500.41 according to - Moderate or Mild Irritation
eye irritation: in vivo · Screening · other guideline: Draize: Appraisal of the safety of chemicals in foods, drugs and cosmetics. In Dermal toxicity p. 46-59 1959 according to
Source: US EPA CompTox dashboard
Related literature
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- MFDS (Korea) cosmetic ingredient register
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata