Ingredient Dictionary

PHENOXYETHYL ISOBUTYRATE

2-Phenoxyethyl isobutyrate is an aromatic ether.

Definition

2-Phenoxyethyl isobutyrate is an aromatic ether.

Source: PubChem

US FDA substance register · UNII 43ENB1627Z · registered name 2-PHENOXYETHYL ISOBUTYRATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

PHENOXYETHYL ISOBUTYRATEINCIPropanoic acid, 2-methyl-, 2-phenoxyethyl esterSynonym

CAS No.chemical registry number: 103-60-6
EC No.EU chemical inventory number: 203-127-1
DTXSIDUS EPA chemical ID: DTXSID7042279
DTXCIDUS EPA compound ID: DTXCID5022279

IUPAC: 2-Phenoxyethyl 2-methylpropanoate
Molecular formula: C12H16O3
Molecular weight: 208.257 g/mol

Measured properties

Appearance: liquid
Colour: colourless, clear
Molecular weight: 208.26 (est.)

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 190 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance186
Deodorizer2
Flavouring and nutrient2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 1 eye studies are on record.

Classed as low3

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 4 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: OECD Guideline 411 (Subchronic Dermal Toxicity: 90-Day Study) equivalent or similar to
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to OECD Guideline 406 (Skin Sensitisation)
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to