Ingredient Dictionary

PHENOXYISOPROPANOL

Korean limit: 1.0%

Definition

Phenoxyisopropanol is the aromatic ether alcohol that conforms to the formula:

US FDA substance register · UNII 87CZY0NY1A · registered name PHENOXYISOPROPANOL · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Stops microbes growing in the productPRESERVATIVEBase that dissolves other ingredientsSOLVENT

Safety & regulatory references

Restricted: South Korea · Taiwan · United Kingdom
Allowed preservative: Taiwan · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS)

Argentina · Brazil

Field of application and/or use : Only rinse products. Not for use in products for oral hygiene.
Maximum concentration permitted at final product : 2%
Maximum concentration permitted at final product : 1.0%
Other limitations and requirements : Only products RINSE to n

ASEAN

Field of application and/or use : • Rinse-off products only • Prohibited in oral hygiene products
Maximum authorised concentration in the finished cosmetic product : 2%
Other limitations and requirements : As a preservative, see Annex VI, Part 1, No 43

China

Maximum concentration : 2%
Maximum concentration : 1%

European Union

Product Type, body parts : Rinse-off products Not to be used in oral products
Maximum concentration in ready for use preparation : 2%
Other : For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product
Product Type, body parts : Only for rinse-off products
Maximum concentration in ready for use preparation : 1.0%

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex III (restricted substances), entry 54 · maximum concentration 2% · applies to Rinse-off products Not to be used in oral products

Source: EU restricted substances (Annex III)

EU Cosmetics Regulation, Annex V (allowed preservatives), entry 43 · maximum concentration 1.0% · applies to Only for rinse-off products

Source: EU allowed preservatives (Annex V)

Restriction III/54 V/43

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name フェノキシイソプロパノール: 本品は、次の化学式で表される芳香族エーテルアルコールである。

Source: JCIA labelling names (Japan)

Names & identifiers

PHENOXYISOPROPANOLINCI페녹시이소프로판올Korean label name (MFDS standard)2-Propanol, 1-phenoxy-SynonymフェノキシイソプロパノールJapanese labelling name

CAS No.chemical registry number: 770-35-4
EC No.EU chemical inventory number: 212-222-7
DTXSIDUS EPA chemical ID: DTXSID9027312
DTXCIDUS EPA compound ID: DTXCID407312

IUPAC: 1-Phenoxypropan-2-ol
Molecular formula: C9H12O2
Molecular weight: 152.193 g/mol

Measured properties

Appearance: liquid
Colour: colourless
Melting/freezing point: &amp, lt, 25 ℃
Initial boiling point and range: 242.7 ℃
Flash point: 115 ℃(calc.)
Flammability (solid, gas): flammable
Vapour pressure: 0.01 hPa (@ 20 ℃, est.)
Water solubility: 11000 ㎎/ℓ (@ 25 ℃)
Vapour density: 5.25
Relative density: 1.06 (@ 20 ℃)
n-Octanol/water partition coefficient (Kow): 1.52 (est.)
Auto-ignition temperature: 480 ℃ (calc.)
Viscosity: 22.7 cP (@ 25 ℃)
Molecular weight: 152.19

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 58 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Solvent41
Coalescing agent4
Film former4
Preservative3
Anti-adhesive/cohesive2
Surfactant (surface active agent)1
Processing aids not otherwise specified1
Solubility enhancer1

1 other uses

Lubricating agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

5 skin studies and 4 eye studies are on record.

Classed as low5

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 9 studies

Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EPA OTS 798.4100 (Skin Sensitisation) according to other guideline: MAFF Dermal Sensitization Study, 1985.
Not classified
Skin Irritation · Screening
Not classified
Skin Sensitization · Screening
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Severe Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Category 1
Eye Irritation · Screening
Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Category 6.4A (Category 2A)
Eye Irritation · Read Across