Phenylmethanesulfonyl fluoride is an acyl fluoride with phenylmethanesulfonyl as the acyl group.
Definition
Phenylmethanesulfonyl fluoride is an acyl fluoride with phenylmethanesulfonyl as the acyl group. It has a role as a serine proteinase inhibitor. It is functionally related to a phenylmethanesulfonic acid.
Source: PubChem
US FDA substance register · UNII 57KD15003I · registered name PHENYLMETHANESULFONYL FLUORIDE · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 329-98-6
- EC No.EU chemical inventory number
- 206-350-2
- EC No.EU chemical inventory number
- 206-350-2 (I)
- DTXSIDUS EPA chemical ID
- DTXSID6059819
- DTXCIDUS EPA compound ID
- DTXCID2038605
- IUPAC
- Phenylmethanesulfonyl fluoride
- Molecular formula
- C7H7FO2S
- Molecular weight
- 174.19 g/mol
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Category 8.2C (Category 1C)
Skin Irritation · Read Across - Category 8.3A (Category 1)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Assessing the Efficacy of Protease Inactivation for the Preservation of Bioactive Amphibian Skin Peptides · 2024
- Hemorrhagic metalloproteinase, Cc HSM‐III, isolated from Cerastes cerastes venom: Purification and biochemical characterization · 2017
- Effect of the enzyme inhibitor, phenylmethylsulfonyl fluoride, on the IOP profiles of topical anandamides. · 2002
- Metabolism of all-trans-retinol in normal human cell strains and squamous cell carcinoma (SCC) lines from the oral cavity and skin: reduced esterification of retinol in SCC lines. · 1998
- Purification and characterization of an extracellular proteinase from Hendersonula toruloidea · 1990