Phloretin is a member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'.
How much products actually contain
No product states its amount yet.
Of the products containing it, 4 list it before the 1% line and 19 after it (usually 1% or less).
Products using this ingredient
12 of 23 confirmed · likeliest to carry enough first · See all 23
ROUND LABROUND LAB Soybean Panthenol Toner 250ml
BubbleBubble Float On
The Face ShopUltimate Multi Vita 10% Serum 50ml
ISNTREEYam Vegan Barrier Milky Toner
AnuaAnua Niacinamide Tranexamic Acid Brightening Booster Toner
CCLIME BEAUTYCore Set Glow Boost Toner
WELLAGEReal Hyaluronic Blue 100 Ampoule 75ml (2-Pack)
WELLAGEReal Hyaluronic Blue 100 Ampoule 100ml
WELLAGEReal Hyaluronic Blue 100 Ampoule
WELLAGEWELLAGE Real Hyaluronic Blue 100 Ampoule
WELLAGEWELLAGE Real Hyaluronic Blue 100 Ampoule 100ml
WELLAGEWELLAGE Best Sellers One-Time Special Offer
Definition
Phloretin is a member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'. It has a role as an antineoplastic agent and a plant metabolite. It is functionally related to a dihydrochalcone.
Source: PubChem
US FDA substance register · UNII S5J5OE47MK · registered name PHLORETIN · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name フロレチン: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 60-82-2
- EC No.EU chemical inventory number
- 200-488-7
- DTXSIDUS EPA chemical ID
- DTXSID6022393
- DTXCIDUS EPA compound ID
- DTXCID702393
- IUPAC
- 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
- Molecular formula
- C15H14O5
- Molecular weight
- 274.272 g/mol
Measured properties
- Appearance
- Solid · Pearl white powder, Sweet aroma
- Melting point
- 263.5 °C
- Solubility
- 0.123 mg/mL at 16 °C · Slightly soluble in water
- Melting/freezing point
- 263 ℃
- Initial boiling point and range
- 467.47 ℃
- Water solubility
- 123 ㎎/ℓ (16deg C)
- n-Octanol/water partition coefficient (Kow)
- 3.510
- Molecular weight
- 274.27
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Flavouring and nutrient2
- Antioxidant1
- Pharmaceutical (EPA)1
Source: US EPA CompTox dashboard
Related literature
- Dermatological applications of the flavonoid phloretin. · 2020
- Design of Antiacne Gel Containing Phloretin. · 2026
- Transdermal Delivery of Phloretin by Gallic Acid Microparticles · 2023
- Phloretin Inhibits Quorum Sensing and Biofilm Formation in Serratia marcescens · 2023
- Phloretin as both a substrate and inhibitor of tyrosinase: Inhibitory activity and mechanism. · 2020
Linked databases 18
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese