定义
Phlorhizin
美国FDA 物质登记 · UNII CU9S17279X · 登记名称 PHLORIZIN · 单一化学物质
化妆品中的作用
保持肌肤良好状态（CosIng 泛分类）SKIN CONDITIONING
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
Other restriction: ban substances that deplete the ozone layer
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
PHLORIDZININCI
- CAS No.化学物质登记号
- 60-81-1
- EC No.欧盟化学品目录编号
- 200-487-1
- DTXSID美国EPA化学品编号
- DTXSID3075339
- DTXCID美国EPA化合物编号
- DTXCID1042738
- IUPAC
- 3,5-Dihydroxy-2-[3-(4-hydroxyphenyl)propanoyl]phenyl beta-D-glucopyranoside
- 分子式
- C21H24O10
- 分子量
- 436.413 g/mol
实测物性
- 熔点/凝固点
- 110 ℃(估算值)
- 初沸点和沸程
- 596.94 ℃(估算值)
- 闪点
- 270.7 ℃(估算值)
- 蒸气压
- 0.0000000000000000316 ㎜Hg (at 25C , 估算值)
- 溶解度
- 1000 ㎎/ℓ (at 22C)
- 正辛醇/水分配系数（Kow）
- 0.720 (估算值)
- 分子量
- 344.32
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: 韩国安全保健公团 安全数据表
产品实际使用的用途
刺激与致敏试验记录
记录有皮肤试验 1 项、眼部试验 2 项。
归类为低1 项
试验结论基本一致（100%）。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 3 项试验
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 442B (Skin Sensitization: Local Lymph Node Assay: BrdU-ELISA) - Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 438 (Isolated Chicken Eye Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage) according to EU method B.48 (Isolated chicken eye test method for identifying occular corrosives and severe irritants) according to - Studies Indicate No Significant Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage) according to
来源: 美国EPA CompTox
相关文献
- Therapeutic potential of phloridzin carbomer gel for skin inflammatory healing in atopic dermatitis · 2025
- Evaluation of in vitro Skin Permeation of Enzymatically Synthesized Phloridzin Acetates from Emulsions and Liposomes Dispersed in Gel · 2022
- Novel Docosahexaenoic Acid Ester of Phloridzin Inhibits Proliferation and Triggers Apoptosis in an In Vitro Model of Skin Cancer · 2018
- Apple phenolics and their contribution to enzymatic browning reactions · 2014
- Synthesis, Antioxidant and Antimicrobial Activity of a New Phloridzin Derivative for Dermo-Cosmetic Applications · 2012