Definition
Piceatannol is a stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5. It has a role as a geroprotector, a hypoglycemic agent, an antineoplastic agent, a protein kinase inhibitor, a tyrosine kinase inhibitor, an apoptosis inducer and a plant metabolite. It is a polyphenol, a member of catechols, a member of resorcinols and a stilbenol. It derives from a hydride of a trans-stilbene.
Source: PubChem
US FDA substance register · UNII 6KS3LS0D4F · registered name PICEATANNOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ピセアタンノール: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 10083-24-6
- DTXSIDUS EPA chemical ID
- DTXSID6040587
- DTXCIDUS EPA compound ID
- DTXCID4020587
- IUPAC
- 4-[(E)-2-(3,5-Dihydroxyphenyl)ethen-1-yl]benzene-1,2-diol
- Molecular formula
- C14H12O4
- Molecular weight
- 244.246 g/mol
Measured properties
- Appearance
- Solid
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Antioxidant1
Source: US EPA CompTox dashboard
Related literature
- Exploring the therapeutic potential of naturally occurring piceatannol in non‐communicable diseases · 2023
- Piceatannol, a metabolite of resveratrol, attenuates atopic dermatitis by targeting Janus kinase 1. · 2022
- Piceatannol, a resveratrol analog, attenuates Dermatophagoides farinae-induced atopic dermatitis like symptoms in NC/Nga mice · 2021
- Piceatannol: A Natural Stilbene for the Prevention and Treatment of Cancer. · 2020
- A Review of the Pharmacological Effects of Piceatannol on Cardiovascular Diseases · 2014
Linked databases 15
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese