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Ingredientes

Diccionario de ingredientes

PICRAMIC ACID

Límite en Corea
0.6%
Estructura molecular

Definición

Registro de sustancias de la FDA (EE. UU.) · UNII 5VDQ7GK8L3 · nombre registrado PICRAMIC ACID · sustancia química única

Fuente: Identificador único de ingredientes de la FDA (UNII)

Funciones cosméticas

Tiñe el cabelloHAIR DYEING

Referencias de seguridad y regulación

Restringido
Corea del Sur · Taiwán

Fuente: Información regulatoria cosmética del MFDS (Corea)

ASEAN

  • Field of application and/or use : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
  • Maximum authorised concentration in the finished cosmetic product : (b) 0.6%
  • Other limitations and requirements : (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.6 % (a) and (b): The direction for use “wear suitable gloves” must be included in label or leaflet text.
  • Conditions of use and warning which must be printed on the labels : (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past (a) & (b) Do not use to dye eyelashes or eyebrows

Unión Europea

  • Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
  • Maximum concentration in ready for use preparation : (b) 0.6 %
  • Other : (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,6 %
  • Wording of conditions of use and warnings : (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.”

Fuente: Información regulatoria cosmética del MFDS (Corea)

Sin clasificación en la lista GHS de sustancias tóxicas de Corea · sustancia química existente

Fuente: Registro GHS de sustancias tóxicas de Corea (NIER)

Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Picramic acid and sodium picramate

Fuente: Lista de ingredientes CosIng (UE)

Reviewed by CIR: Amended Safety Assessment of Sodium Picramate and Picramic Acid

Fuente: Cosmetic Ingredient Review (CIR, EE. UU.)

Más datos: nombres, identificadores, propiedades, ensayos y literatura

Nombres e identificadores

PICRAMIC ACIDINCI피크라민산Nombre en etiquetas coreanas (estándar MFDS)Phenol, 2-amino-4,6-dinitro-Sinónimo
CAS No.número de registro químico
96-91-3
EC No.número de inventario químico de la UE
202-544-6
DTXSIDidentificador químico de la EPA (EE. UU.)
DTXSID5024479
DTXCIDidentificador de compuesto de la EPA (EE. UU.)
DTXCID904479
IUPAC
2-Amino-4,6-dinitrophenol
Fórmula molecular
C6H5N3O5
Peso molecular
199.122 g/mol

Propiedades medidas

Aspecto
2-amino-4,6-dinitrophenol, wetted with not less than 20% water appears as dark red needles or prisms. Red crystals. Water insoluble. Explosive in the dry state but desensitized by wetting. Easily ignited and once ignited burn readily. · 2-amino-4,6-dinitrophenol appears as dark red needles or prisms. Red crystals. Water insoluble. Explosive in the dry state but desensitized by wetting. Easily ignited and once ignited burn readily.
Punto de fusión
336 °F (NTP, 1992) · 169 °C
Solubilidad
less than 1 mg/mL at 68.9 °F (NTP, 1992) · @ 22-25 °C, 0.065 g dissolves in 100 ml H2O
Coeficiente de reparto n-octanol/agua (Kow)
0.93
Peso molecular
192.12 (HSDB)

Valores medidos en la sustancia en sí. Los datos de KOSHA son una referencia para redactar y revisar fichas de seguridad, no una especificación de una materia prima comercial.

Fuente: PubChem · Fichas de datos de seguridad de KOSHA (Corea)

Para qué lo usan los productos

Usos de los 1 productos declarados ante la EPA de EE. UU. con este ingrediente. Incluye productos que no son cosméticos, así que las primeras filas son sus usos principales.

  • Dye1

Fuente: Panel CompTox de la EPA

Estudios de irritación y sensibilización

Constan 6 estudios en piel y 1 en ojos.

Clasificado como muy irritante3Clasificado como bajo1

Las conclusiones de los estudios coinciden en general (75%). Son ensayos de la materia prima en sí; la irritación a la cantidad de un producto terminado es otra cuestión.

Ver los 7 estudios
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline:
  • Classification not possible
    Skin Irritation · Screening
  • Classification not possible
    Skin Sensitization · Screening
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: as below
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · other guideline: according to
  • Category 6.5B (Category 1)
    Skin Sensitization · Read Across
  • Classification not possible
    Eye Irritation · Screening

Fuente: Panel CompTox de la EPA

Literatura relacionada

Bases de datos vinculadas 20