この成分は何ですか?

이 원료는 다음의 구조를 갖는 치환된 페놀이다.

成分一覧

成分辞典

PICRAMIC ACID

韓国の配合上限: 0.6%

定義

米国FDA 物質登録 · UNII 5VDQ7GK8L3 · 登録名 PICRAMIC ACID · 単一の化学物質

出典: 米国FDA 物質識別番号（UNII）

化粧品での役割

髪を染めるHAIR DYEING

安全性・規制情報

制限: 韓国

出典: 韓国食薬処化粧品規制情報

ASEAN

Field of application and/or use : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Maximum authorised concentration in the finished cosmetic product : (b) 0.6%
Other limitations and requirements : (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.6 % (a) and (b): The direction for use “wear suitable gloves” must be included in label or leaflet text.
Conditions of use and warning which must be printed on the labels : (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past (a) & (b) Do not use to dye eyelashes or eyebrows

台湾

※ 染髮產品之限量標準：係指該成分依產品使用說明書混合後之最高允許使用量。
※ 化粧品之外包裝或容器，應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者，應於標籤、仿單或以其他方式刊載之。
※ 本表所稱之口腔製劑，包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
※ 化粧品宣稱效能者，須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。
用途 : 使用限制
最大配合量 : (a)氧化性染髮產品 : 0.6%
(b)非氧化性染髮產品 : 0.6%

欧州連合

Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Maximum concentration in ready for use preparation : (b) 0.6 %
Other : (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,6 %
Wording of conditions of use and warnings : (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.â€

出典: 韓国食薬処化粧品規制情報

韓国の有害物質GHS分類なし · 既存化学物質

出典: 韓国有害物質GHS情報（環境公団）

Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Picramic acid and sodium picramate

出典: EU CosIng 成分リスト

Reviewed by CIR: Amended Safety Assessment of Sodium Picramate and Picramic Acid

出典: 米国CIR 安全性評価

詳しい資料 — 表示名・識別番号・物性・試験記録・文献

別名・識別情報

PICRAMIC ACIDINCI피크라민산韓国の表示名（食薬処標準名）Phenol, 2-amino-4,6-dinitro-別名

CAS No.化学物質登録番号: 96-91-3
EC No.EU化学物質目録番号: 202-544-6
DTXSID米国EPA化学物質番号: DTXSID5024479
DTXCID米国EPA化合物番号: DTXCID904479

IUPAC: 2-Amino-4,6-dinitrophenol
分子式: C6H5N3O5
分子量: 199.122 g/mol

測定された物性

性状: 2-amino-4,6-dinitrophenol, wetted with not less than 20% water appears as dark red needles or prisms. Red crystals. Water insoluble. Explosive in the dry state but desensitized by wetting. Easily ignited and once ignited burn readily. · 2-amino-4,6-dinitrophenol appears as dark red needles or prisms. Red crystals. Water insoluble. Explosive in the dry state but desensitized by wetting. Easily ignited and once ignited burn readily.
融点: 336 °F (NTP, 1992) · 169 °C
溶解性: less than 1 mg/mL at 68.9 °F (NTP, 1992) · @ 22-25 °C, 0.065 g dissolves in 100 ml H2O
n-オクタノール/水分配係数（Kow）: 0.93
分子量: 192.12 (HSDB)

物質そのものを測定した値です。安全保健公団（KOSHA）の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。

出典: PubChem · 韓国安全保健公団 SDS

製品が実際に使っている用途

米国EPAにこの成分を届け出た製品1件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。

Dye1

出典: 米国EPA CompTox

刺激・感作試験の記録

皮膚試験6件・眼試験1件の記録があります。

刺激が強いと分類3件低いと分類1件

試験の結論はおおむね一致しています（75%）。原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。

試験7件をすべて見る

High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline:
Classification not possible
Skin Irritation · Screening
Classification not possible
Skin Sensitization · Screening
High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: as below
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: according to
Category 6.5B (Category 1)
Skin Sensitization · Read Across
Classification not possible
Eye Irritation · Screening