Ingredient Dictionary

PIGMENT ORANGE 5

D&C Orange No.

Definition

D&C Orange No. 17 can cause cancer according to The Food and Drug Administration (FDA).

Source: PubChem

US FDA substance register · UNII E27LT0986O · registered name DINITROANILINE ORANGE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Adds colourCOLORANT

Safety & regulatory references

Banned: Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea · United Kingdom
Restricted: Japan
Allowed colourant: United States

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · Health Canada Cosmetic Ingredient Hotlist · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS) · US FDA prohibited and restricted ingredients

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 397

Source: EU prohibited substances (Annex II)

Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics

Source: Health Canada Cosmetic Ingredient Hotlist

Restriction II/397 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

PIGMENT ORANGE 5INCI2-Naphthalenol, 1-[(2,4-dinitrophenyl)azo]-Synonym피그먼트등색5호Korean label name (MFDS standard)

CAS No.chemical registry number: 3468-63-1
EC No.EU chemical inventory number: 222-429-4
DTXSIDUS EPA chemical ID: DTXSID6029258
DTXCIDUS EPA compound ID: DTXCID10809869

IUPAC: 1-[(2,4-Dinitrophenyl)diazenyl]naphthalen-2-ol
Molecular formula: C16H10N4O5
Molecular weight: 338.279 g/mol

Measured properties

Appearance: Dry Powder, Liquid, CBI · Reddish shade of orange
Melting point: 302 °C
Density: 1.52 No temp
Water solubility: 0.1336 ㎎/ℓ
Relative density: 1.6
n-Octanol/water partition coefficient (Kow): 5.72
Molecular weight: 338.3

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Pigment7
Dye2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 1 eye studies are on record.

Classed as highly irritating3Classed as low2

The study conclusions largely agree (60%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 4 studies

Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to