Piperonylic acid is a member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a carboxy group at position 5.
定义
Piperonylic acid is a member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a carboxy group at position 5. It is a natural product isolated from several plant species. It is a selective mechanism-based inactivator of the trans-cinnamate 4-hydroxylase enzyme and exhibits antifungal and skin wound healing properties. It has a role as an EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor, an antifungal agent, a vulnerary and a plant metabolite. It is a monocarboxylic acid, an aromatic carboxylic acid and a member of benzodioxoles. It is a conjugate acid of a piperonylate.
来源: PubChem
美国FDA 物质登记 · UNII QX3V1NO0KH · 登记名称 PIPERONYLIC ACID · 单一化学物质
Piperonylic Acid is the organic compound that conforms to the formula.
化妆品中的作用
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 ピペロニル酸: 本品は、次の化学式で表される有機化合物である。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
- CAS No.化学物质登记号
- 94-53-1
- EC No.欧盟化学品目录编号
- 202-342-8
- DTXSID美国EPA化学品编号
- DTXSID6059104
- DTXCID美国EPA化合物编号
- DTXCID7048902
- IUPAC
- 2H-1,3-Benzodioxole-5-carboxylic acid
- 分子式
- C8H6O4
- 分子量
- 166.132 g/mol
产品实际使用的用途
这是向美国 EPA 申报含该成分的 2 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Humectant1
- Softener and conditioner1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 1 项、眼部试验 0 项。
试验结论基本一致（100%）。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 1 项试验
- SkinSens1
Skin Sensitization · QSAR Predicted
来源: 美国EPA CompTox
相关文献
- Green Synthesis of Zinc Oxide Nanoparticles Using Piperonylic Acid: Characterization and Antibacterial Activity · 2026
- Piperonylic Acid Promotes Hair Growth by Activation of EGFR and Wnt/β-Catenin Pathway · 2024
- Accelerative action of topical piperonylic acid on mice full thickness wound by modulating inflammation and collagen deposition · 2021
- Piperonylic acid stimulates keratinocyte growth and survival by activating epidermal growth factor receptor (EGFR) · 2018