Piroctone is a cyclic hydroxamic acid that consists of 1-hydroxypyridin-2-one bearing methyl and 2,4,4-trimethylpentyl substtituents at positions 4 and 6 respectively.
定義
米国FDA 物質登録 · UNII R49EFA73Q7 · 登録名 PIROCTONE · 単一の化学物質
Piroctone is a cyclic hydroxamic acid that consists of 1-hydroxypyridin-2-one bearing methyl and 2,4,4-trimethylpentyl substtituents at positions 4 and 6 respectively. It has a role as an antiseborrheic. It is a cyclic hydroxamic acid, a pyridone and a hydroxypyridone antifungal drug.
出典: PubChem
Piroctone is the organic compound that conforms to the formula
化粧品での役割
微生物の増殖を抑えるANTIMICROBIAL製品中の微生物の増殖を防ぐPRESERVATIVE
安全性・規制情報
Restriction V/35
出典: EU CosIng 成分リスト
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
PIROCTONEINCI2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-別名
- CAS No.化学物質登録番号
- 50650-76-5
- DTXSID米国EPA化学物質番号
- DTXSID2048298
- DTXCID米国EPA化合物番号
- DTXCID7028273
- IUPAC
- 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one
- 分子式
- C14H23NO2
- 分子量
- 237.343 g/mol
測定された物性
- 性状
- 固体
- 融点・凝固点
- 108 ℃
- 初留点および沸点範囲
- 379.31 ℃
- 蒸気圧
- 1.14E-7 ㎜Hg (25℃)
- 溶解度
- 18.75 ㎎/ℓ (25℃)
- 蒸気密度
- 8.19261304798067
- 比重
- 10.29
- n-オクタノール/水分配係数（Kow）
- 3.71
- 分子量
- 237.34
物質そのものを測定した値です。安全保健公団（KOSHA）の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。
出典: 韓国安全保健公団 SDS
関連文献
- Investigation of complexation behavior of piroctone olamine salt with Fe(III) ions and influence on antifungal activity · 2026
- Synergistic Antifungal Activity and Mechanism of Piroctone Olamine and Sorbitan Caprylate against Malassezia restricta. · 2026
- Characterization of piroctone olamine for topical delivery to the skin · 2023
- Investigation of piroctone olamine delivery to the skin from single, binary and ternary solvent systems · 2023
- Study of the effectiveness of shampoo application (combination of 3% salicylic acid, piroctone olamine and panthenol) as an external therapy of scalp psoriasis · 2023