Piroctone is a cyclic hydroxamic acid that consists of 1-hydroxypyridin-2-one bearing methyl and 2,4,4-trimethylpentyl substtituents at positions 4 and 6 respectively.
定义
美国FDA 物质登记 · UNII R49EFA73Q7 · 登记名称 PIROCTONE · 单一化学物质
Piroctone is a cyclic hydroxamic acid that consists of 1-hydroxypyridin-2-one bearing methyl and 2,4,4-trimethylpentyl substtituents at positions 4 and 6 respectively. It has a role as an antiseborrheic. It is a cyclic hydroxamic acid, a pyridone and a hydroxypyridone antifungal drug.
来源: PubChem
Piroctone is the organic compound that conforms to the formula
化妆品中的作用
抑制微生物生长ANTIMICROBIAL防止产品中微生物滋生PRESERVATIVE
安全与法规参考
Restriction V/35
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
PIROCTONEINCI2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-同义名
- CAS No.化学物质登记号
- 50650-76-5
- DTXSID美国EPA化学品编号
- DTXSID2048298
- DTXCID美国EPA化合物编号
- DTXCID7028273
- IUPAC
- 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one
- 分子式
- C14H23NO2
- 分子量
- 237.343 g/mol
实测物性
- 性状
- 固体
- 熔点/凝固点
- 108 ℃
- 初沸点和沸程
- 379.31 ℃
- 蒸气压
- 1.14E-7 ㎜Hg (25℃)
- 溶解度
- 18.75 ㎎/ℓ (25℃)
- 蒸气密度
- 8.19261304798067
- 比重
- 10.29
- 正辛醇/水分配系数（Kow）
- 3.71
- 分子量
- 237.34
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: 韩国安全保健公团 安全数据表
相关文献
- Investigation of complexation behavior of piroctone olamine salt with Fe(III) ions and influence on antifungal activity · 2026
- Synergistic Antifungal Activity and Mechanism of Piroctone Olamine and Sorbitan Caprylate against Malassezia restricta. · 2026
- Characterization of piroctone olamine for topical delivery to the skin · 2023
- Investigation of piroctone olamine delivery to the skin from single, binary and ternary solvent systems · 2023
- Study of the effectiveness of shampoo application (combination of 3% salicylic acid, piroctone olamine and panthenol) as an external therapy of scalp psoriasis · 2023