PLACENTAL ENZYMES

Placental Enzymes is a mixture of enzymes obtained from an aqueous extraction of animal placentas.

Restriction Please consider whether entry 419 of Annex II to the Cosmetics Regulation 1223/2009 is applicable. According to entry 419, category 1 material and Category 2 material as defined in Articles 4 and 5 respectively of Regulation (EC) No 1774/2002, and ingredients derived therefrom are prohibited in cosmetics products. Regulation (EC) No 1774/2002 has been repealed and replaced by Regulation No. 1069/2009. For Category 1 and 2 materials in Regulation No. 1069/2009, please see Article 8 and 9, respectively.

Source: EU CosIng ingredient list

Reviewed by CIR: Final Report on the Safety Assessment of Human Placental Protein, Hydrolyzed Human Placental Protein, Human Placental Enzymes, Human Placental Lipids, Human Umbilical Extract, Placental Protein, Hydrolyzed Placental Protein, Placental Enzymes, Placental Lipids and Umbilical Extract

Source: US Cosmetic Ingredient Review (CIR)

CIR reviewed this ingredient and flagged its status as: CIR insufficient data ingredients - use not supported (insufficient data or use not supported — CIR's own classification, not a full safety-as-used conclusion).

Source: US Cosmetic Ingredient Review (CIR)