What is this ingredient?

미국 FDA 물질 등록 · UNII DG195GP57P · 등록명 POLYGLYCERYL-2 DIISOSTEARATE · 단일 화학물질

All ingredients

Ingredient Dictionary

POLYGLYCERYL-2 DIISOSTEARATE

How much products actually contain

No product states its amount yet.

Of the products containing it, 152 list it before the 1% line and 19 after it (usually 1% or less).

Products using this ingredient

12 of 159 confirmed · likeliest to carry enough first · See all 159

Definition

US FDA substance register · UNII DG195GP57P · registered name POLYGLYCERYL-2 DIISOSTEARATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Diester of diglycerol and isostearic acid

Cosmetic roles

Mixes and holds oil and water togetherSURFACTANT - EMULSIFYING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ジイソステアリン酸ポリグリセリル－２: 本品は、イソステアリン酸（＊）とジグリセリン（＊）のジエステルである。

Source: JCIA labelling names (Japan)

JCIA labelling name セスキイソステアリン酸ポリグリセリル－２: 本品は、イソステアリン酸（＊）とジグリセリンのモノ及びジエステルの混合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

POLYGLYCERYL-2 DIISOSTEARATEINCI폴리글리세릴-2다이아이소스테아레이트Korean label name (MFDS standard)폴리글리세릴-2세스퀴이소스테아레이트Korean label name (MFDS standard)Isooctadecanoic acid, diester with oxybis[propanediol]SynonymPOLYGLYCERYL-2 SESQUIISOSTEARATESynonymジイソステアリン酸ポリグリセリル－２Japanese labelling name

CAS No.chemical registry number: 63705-03-3
CAS No.chemical registry number: 67938-21-0
EC No.EU chemical inventory number: 267-821-6
DTXSIDUS EPA chemical ID: DTXSID301021513
DTXCIDUS EPA compound ID: DTXCID501506529

IUPAC: Oxybis(2-hydroxypropane-3,1-diyl) bis(16-methylheptadecanoate)
Molecular formula: C42H82O7
Molecular weight: 699.111 g/mol

Measured properties

Appearance: liquid
pH: 6.6~6.8
Melting/freezing point: -10 ℃
Flash point: 200 ℃
Vapour pressure: 0 ㎩ (20℃)
Water solubility: 3 ㎎/ℓ (20℃, pH: 6.6~6.8)
Vapour density: 0.941 g/㎤
Relative density: 0.941 g/cm³ (20℃)
n-Octanol/water partition coefficient (Kow): 14 (log Pow, 20℃)
Viscosity: 571 mPa S

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Emulsifier2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 3 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 5 studies

Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Ambiguous
eye irritation: in vivo · Screening · other guideline: Federal Register 38, No. 187, 27.9.1973, p 27019 according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Act, 16 CFR, Section 1500.42 according to