定义
美国FDA 物质登记 · UNII ZV5114S322 · 登记名称 POTASSIUM BORATE · 单一化学物质
Potassium Borate is the inorganic salt that conforms to the formula:
化妆品中的作用
稳定 pHBUFFERING
安全与法规参考
- 限用·禁用
- 欧盟
来源: 韩国食药处 化妆品法规信息
阿根廷 · 巴西
- Field of application and/or use : (a)Talc (b) Products for oral hygiene (c) Other products (excluding bath products and hair undulation)
- Maximum concentration permitted at final product : (a) 5% (m/m calculated as boric acid) (b) 0,1% (m/m calculated as boric acid) (c) 3% (m/m calculated as boric acid)
- Other limitations and requirements : a) No use in products for children under 3 years. Do not use on broken or irritated skin if the tenor of soluble free borates exceed 1,5% (calculated as boric acid, m / m) b) No use in products for children under 3 years. c) No use in products for children under 3 years. Do not use on broken or irritated skin if the concentration of soluble borates exceed 1,5% (calculated as boric acid, m / m)
- Use conditions and warnings that must appear on the label : a), b) and c) For products for adult use: "Do not use in children" For products aimed at children: "Do not use in children under 3 years" a) Do not use on broken or irritated skin b) Do not ingest c) Do not use on broken or irritated skin
- Field of application and/or use : (a) Products for bath (b) Products for waving of hair
- Maximum concentration permitted at final product : (a) 18% (m/m calculated as boric acid) (b) 8% (m/m calculated as boric acid)
- Other limitations and requirements : a) No use in products for children under 3 years.
- Use conditions and warnings that must appear on the label : a), b) and c) For products for adult use: "Do not use in children" For products aimed at children: "Do not use in children under 3 years" b) Rinse thoroughly
东盟
- Field of application and/or use : (a) Talc (b) Products for oral hygiene (c) Other products (excluding bath products and hair waving products)
- Maximum authorised concentration in the finished cosmetic product : (a) 5% (by mass/mass as boric acid) (b) 0.1% (by mass/mass as boric acid) (c) 3% (by mass/mass as boric acid)
- Other limitations and requirements : (a) 1. Not to be used in products for children under 3 years of age 2. Not to be used on peeling or irritated skin if the concentration of free soluble borates exceeds 1.5% (by mass/mass as boric acid) (b) Not to be used in products for children under 3 years of age (c) 1. Not to be used in products for children under 3 years of age 2. Not to be used on peeling or irritated skin if the concentration of free soluble borates exceeds 1.5% (by mass/mass as boric acid)
- Conditions of use and warning which must be printed on the labels : (a) 1. Not to be used in products for children under 3 years of age 2. Not to be used on peeling or irritated skin (b) 1. Not to be swallowed 2. Not to be used in products for children under 3 years of age (c) 1. Not to be used in products for children under 3 years of age 2. Not to be used on peeling or irritated skin
- Field of application :
- Other limitations and requirements :
加拿大
- Conditions of Use by product type : (a) As a pH adjuster (b) Other cosmetics
- Maximum Concentration Permitted : ((a) 0.1% (b) 5%
- Warnings and Cautionary Statements: (to the effect of) : (b) "Do not use on broken or abraded skin, not to be used by children under three years of age."
来源: 韩国食药处 化妆品法规信息
未列入韩国有毒物质 GHS 分类 · 现有化学物质
Restriction II/1396 · SCCS opinion: Opinion on Boric acid, Borates and Tetraborates; Opinion on Sodium Perborate and Perboric Acid
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
POTASSIUM BORATEINCI포타슘보레이트韩国标示名称(食药处标准名)Boric acid (H2B4O7), dipotassium salt同义名
- CAS No.化学物质登记号
- 1332-77-0
- EC No.欧盟化学品目录编号
- 215-575-5
- DTXSID美国EPA化学品编号
- DTXSID2052782
- DTXCID美国EPA化合物编号
- DTXCID801476771
- IUPAC
- Dipotassium bicyclo[3.3.1]tetraboroxane-3,7-bis(olate)
- 分子式
- B4K2O7
- 分子量
- 233.43 g/mol
实测物性
- 性状
- Liquid, Dry Powder · Pentahydrate: White solid, [Merck Index] White crystalline solid, Odorless, [U.S. Borax MSDS]
- 颜色
- 白色
- 溶解度
- (16.32 w/w % @ 20 ℃)
- 蒸气密度
- 8.06
- 比重
- 1.911 (@ 20 ℃)
- 分子量
- 233.44
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 8 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Intermediate3
- Flux agent2
- pH regulating agent1
- Cleaning agent1
- Lubricating agent1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 4 项、眼部试验 6 项。
归类为低4 项
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 10 项试验
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: This study was carried out to comply with US EPA-FIFRA guidelines at the time and carried out by the US Food and Drug Laboratories to GLP. according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Ambiguous
skin irritation: in vivo · Screening · other guideline: Section 173.240 under Title 49 of the code of Federal Regulations (Federal Register, 1973). according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: This study was carried out to comply with US EPA-FIFRA guidelines at the time and carried out by the US Food and Drug Laboratories to GLP. equivalent or similar to - Severe Irritation
eye irritation: in vivo · Screening · other guideline: EPA, 40 CFR 160 Pesticide Assessment Guidelines, Subdivision F Hazard Evaluation: Human and Domestic Animals, November 1982 according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Severe Irritation
eye irritation: in vivo · Screening · other guideline: EPA, 40 CFR 160 Pesticide Assessment Guidelines, Subdivision F Hazard Evaluation: Human and Domestic Animals, November 1982 . according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: FIFRA (40 CFR 158, 162) according to other guideline: TSCA (40 CFR 798) according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Moderate or Mild Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EPA OPPTS 870.2400 (Acute Eye Irritation) according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
来源: 美国EPA CompTox