Potassium bromate can cause cancer according to The World Health Organization's International Agency for Research on Cancer (IARC).
Definition
Potassium bromate can cause cancer according to The World Health Organization's International Agency for Research on Cancer (IARC).
Source: PubChem
US FDA substance register · UNII 04MB35W6ZA · registered name POTASSIUM BROMATE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea · Taiwan · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex II (prohibited substances), entry 461
Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics
Restriction II/461 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2007-2010
Reviewed by CIR: Final Report on the Safety Assessment of Sodium Bromate and Potassium Bromate
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 7758-01-2
- EC No.EU chemical inventory number
- 231-829-8
- DTXSIDUS EPA chemical ID
- DTXSID6020195
- DTXCIDUS EPA compound ID
- DTXCID40195
- IUPAC
- Potassium bromate
- Molecular formula
- BrKO3
- Molecular weight
- 166.999 g/mol
Measured properties
- Appearance
- Potassium bromate appears as a white crystalline solid. · White solid, [Merck Index] White odorless crystalline solid, Soluble in water, [MSDSonline]
- Odour
- Odorless
- Boiling point
- Decomposes at 698 °F (NTP, 1992)
- Melting point
- 662 °F (NTP, 1992) · 350 °C, decomposes at 370 °C with evolution of oxygen.
- Solubility
- 10 to 50 mg/mL at 66 °F (NTP, 1992) · Solubility (g/100 g water): 3.1 at 0 °C, 6.9 at 20 °C, 13.1 at 40 °C, 22.2 at 60 °C, 33.9 at 80 °C, 49.7 at 100 °C
- Density
- 3.27 (NTP, 1992) - Denser than water, will sink · 3.27 g/cu cm at 17.5 °C
- Stability
- Stable under recommended storage conditions. · /Potassium bromate/ mixtures with sulfur are unstable, and may ignite some hours after preparation, depending on the state of subdivision and atmospheric humidity.
- pH
- The pH of a 1:20 aqueous solution is between 5 and 9
- Colour
- white
- Melting/freezing point
- 350 ℃
- Initial boiling point and range
- 370 ℃
- Water solubility
- 75000 ㎎/ℓ
- Relative density
- 3.218
- Molecular weight
- 167.01
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Oxidizing agent2
- Food preservative (EPA)1
- Leavening agent (EPA)1
- Filler1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) - Category 6.3A (Category 2)
Skin Irritation · Read Across - Classification not possible
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Category 2B
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Protective effects of Urtica dioica on the cerebral cortex damage induced by Potassium bromate in adult male albino rats · 2023
- Uric acid–reducing efficacy of Plectranthus amboinicus (Lour.) Spreng in mice with potassium oxonate-induced hyperuricemia · 2023
- Potassium bromate-induced oxidative stress, genotoxicity and cytotoxicity in the blood and liver cells of mice. · 2022
- Effect of ethanol extract of Aframomum angustifolium seeds on potassium bromate induced liver and kidney damage in Wistar rats · 2020
- Inhibitory effect of bee venom against potassium bromate causing genetic toxicity and biochemical alterations in mice · 2018
Linked databases 25
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- Health Canada Cosmetic Ingredient Hotlist
- IARC carcinogen classification
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Taiwan FDA cosmetic ingredients
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese