Definition
US FDA substance register · UNII 5455FZE9RB · registered name PPG-2 METHYL ETHER ACETATE · single chemical substance
Dipropylene glycol monomethyl ether acetate
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Reviewed by CIR: Final Report on the Safety of PPG-2 Methyl Ether, PPG-3 Methyl Ether, and PPG-2 Methyl Ether Acetate
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 88917-22-0
- DTXSIDUS EPA chemical ID
- DTXSID4029062
Measured properties
- Appearance
- Liquid, CBI · COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR.
- Boiling point
- 209 °C
- Melting point
- -25.5 °C
- Solubility
- Solubility in water, g/100ml: 16 (good)
- Density
- 0.98 g/cm³ · Relative density of the vapour/air-mixture at 20 °C (air = 1): 1.00
- Viscosity
- 1.7 mm²/s at 25 °C
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 97 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance81
- Solvent13
- Adhesion/cohesion promoter1
- Solubility enhancer1
- Coalescing agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 8 studies
- Classification not possible
Skin Sensitization · Screening - Not classified
Skin Irritation · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: U.S. Federal Register, 38:187, Part II, Section 1500.41, 1973 according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not classified
Eye Irritation · Screening - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: U.S. Federal Register, 43:163.81-4, 1978 according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
Linked databases 15
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata