定义
美国FDA 物质登记 · UNII 5455FZE9RB · 登记名称 PPG-2 METHYL ETHER ACETATE · 单一化学物质
Dipropylene glycol monomethyl ether acetate
化妆品中的作用
溶解其他成分的基质SOLVENT
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
Reviewed by CIR: Final Report on the Safety of PPG-2 Methyl Ether, PPG-3 Methyl Ether, and PPG-2 Methyl Ether Acetate
来源: 美国CIR 安全性评估
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
PPG-2 METHYL ETHER ACETATEINCI피피지-2메틸에터아세테이트韩国标示名称(食药处标准名)Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate同义名
- CAS No.化学物质登记号
- 88917-22-0
- DTXSID美国EPA化学品编号
- DTXSID4029062
实测物性
- 性状
- Liquid, CBI · COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR.
- 沸点
- 209 °C
- 熔点
- -25.5 °C
- 溶解性
- Solubility in water, g/100ml: 16 (good)
- 密度
- 0.98 g/cm³ · Relative density of the vapour/air-mixture at 20 °C (air = 1): 1.00
- 黏度
- 1.7 mm²/s at 25 °C
这是对物质本身测得的数值,并非原料商品的规格。
来源: PubChem
产品实际使用的用途
这是向美国 EPA 申报含该成分的 97 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Fragrance81
- Solvent13
- Adhesion/cohesion promoter1
- Solubility enhancer1
- Coalescing agent1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 5 项、眼部试验 3 项。
归类为低4 项
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 8 项试验
- Classification not possible
Skin Sensitization · Screening - Not classified
Skin Irritation · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: U.S. Federal Register, 38:187, Part II, Section 1500.41, 1973 according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not classified
Eye Irritation · Screening - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: U.S. Federal Register, 43:163.81-4, 1978 according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
来源: 美国EPA CompTox