Definition
US FDA substance register · UNII V86KZL3H2Z · registered name PPG-26 · polymer
Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy- (3 mol PO average molar ratio)
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Safety Assessment of Propylene Glycol, Tripropylene Glycol and PPGs as Used in Cosmetics
Reviewed by CIR: Final Report on the Safety Assessment of Propylene Glycol and Polypropylene Glycols
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ＰＰＧ－１２: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－１３: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－１５: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－１７: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－２０: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－２６: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－３０: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－３３: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－３４: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－５１: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－６９: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－７: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－９: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－３: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
JCIA labelling name ＰＰＧ－１６: 本品は、次の化学式で表される酸化プロピレンの重合体である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 25322-69-4
- DTXSIDUS EPA chemical ID
- DTXSID9027863
- Molecular formula
- (C3H6O)nH2O
What products actually use it for
What the 101 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Plasticizer29
- Softener and conditioner14
- Binder12
- Solvent6
- Viscosity modifier6
- Processing aids not otherwise specified6
- Surface modifier4
- Defoamer4
14 other uses
- Hardener3
- Adhesion/cohesion promoter2
- Lubricating agent2
- Pigment2
- Anti-adhesive/cohesive2
- Chemical reaction regulator1
- Surfactant (surface active agent)1
- Waterproofing agent1
- Wetting agent (non-aqueous)1
- Emulsifier1
- Anti-slip agent1
- Dehydrating agent (desiccant)1
- Monomers1
- Fragrance1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 8 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EPA OPPTS 870.2500 (Acute Dermal Irritation) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Register, Volume 38, Number 187, Part II, Section 1500.41 equivalent or similar to - Moderate or Mild Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) Guideline not mentioned in report equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- Oleogel-mediated Topical Administration of Roflumilast and Paclitaxel as a Synergistic Strategy to Combat Imiquimod-induced Psoriasis · 2025
- PPG-11 and PPG-15 Stearyl Ether · 2023
- Curing of UV prints - Assessment of possible toxicological hazard for consumers. · 2021
- A Quasi-experimental Study to Explore the Effect of Barrier Cream on the Peristomal Skin of Patients With a Tracheostomy. · 2018
- Safety Evaluation of Polyethylene Glycol (PEG) Compounds for Cosmetic Use · 2015
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary 2 3 4 5 6 7 8 9 10 11 12 13 14 15
- Korea toxic substances GHS register (NIER)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- Tlooto literature search 2 3 4 5
- US Cosmetic Ingredient Review (CIR) 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS) 2 3 4 5 6 7 8 9 10 11 12 13
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese