Ingredient Dictionary

PRASTERONE

Dehydroepiandrosterone is an androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17.

Definition

Dehydroepiandrosterone is an androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands. It has a role as an androgen, a mouse metabolite and a human metabolite. It is a 3beta-hydroxy-Delta(5)-steroid, a 17-oxo steroid and an androstanoid.

Source: PubChem

US FDA substance register · UNII 459AG36T1B · registered name PRASTERONE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONING

Safety & regulatory references

Banned: Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea · Taiwan

Source: MFDS (Korea) cosmetic regulatory information

Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics

Source: Health Canada Cosmetic Ingredient Hotlist

Restriction II/37

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

PRASTERONEINCI프라스테론Korean label name (MFDS standard)

CAS No.chemical registry number: 53-43-0
EC No.EU chemical inventory number: 200-175-5
DTXSIDUS EPA chemical ID: DTXSID4020379
DTXCIDUS EPA compound ID: DTXCID40379

IUPAC: 3beta-Hydroxyandrost-5-en-17-one
Molecular formula: C19H28O2
Molecular weight: 288.431 g/mol

Measured properties

Appearance: Solid · solid
Melting point: 140-141 °C · 140 - 141 °C
Solubility: 63.5 mg/L (at 25 °C) · 0.0635 mg/mL
Colour: white
Melting/freezing point: ~ (139-141 148-150°C)
Initial boiling point and range: 426.7 ℃(760mmHg)
Flash point: 182.1 ℃
Flammability (solid, gas): not flammable
Vapour pressure: 0.01 ㎩ (25℃ EU Method A.4)
Water solubility: 63.5 ㎎/ℓ (25 °C)
Vapour density: 1.159g/cm3
Relative density: 1.159
n-Octanol/water partition coefficient (Kow): 3.03 (25℃)
Molecular weight: 288.43

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Pharmaceutical (EPA)3
Softener and conditioner1

Source: US EPA CompTox dashboard