Ingredient Dictionary

PROGESTERONE

Progesterone can cause cancer according to an independent committee of scientific and health experts.

Definition

Progesterone can cause cancer according to an independent committee of scientific and health experts.

Source: PubChem

US FDA substance register · UNII 4G7DS2Q64Y · registered name Progesterone · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONING

Safety & regulatory references

Banned: Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Restriction II/194

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

PROGESTERONEINCI프로게스테론Korean label name (MFDS standard)

CAS No.chemical registry number: 57-83-0
EC No.EU chemical inventory number: 200-350-6
DTXSIDUS EPA chemical ID: DTXSID3022370
DTXCIDUS EPA compound ID: DTXCID902370

IUPAC: Pregn-4-ene-3,20-dione
Molecular formula: C21H30O2
Molecular weight: 314.469 g/mol

Measured properties

Appearance: Progesterone is a white powder. Melting point 121 °C. Stable in air. Insoluble in water. A female sex hormone. Low toxicity. · Solid
Odour: Odorless · odourless
Boiling point: 394.13°C (rough estimate)
Melting point: 250 to 252 °F (NTP, 1992) · 128-132
Solubility: less than 1 mg/mL at 66 °F (NTP, 1992) · <0.1 g/100 mL at 19 ºC
Density: 1.171 at 68 °F (NTP, 1992) - Denser than water, will sink · 1.166 g/cu cm at 23 °C
Stability: Progesterone is stable when exposed to air. The drug should be stored in tight, light-resistant containers. · ...stable in air but sensitive to light.
Dissociation constant: Strongest acidic: , Strongest basic: 18.92, -4.8
Colour: white
Melting/freezing point: 121 ℃
Vapour pressure: 0.00000130 ㎜Hg (25℃)
Water solubility: 8.81 g/100㎖ (25℃)
Relative density: 1.166 (23℃)
n-Octanol/water partition coefficient (Kow): 3.87
Molecular weight: 314.47

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Softener and conditioner1

Source: US EPA CompTox dashboard