Propafenone is an aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group.
定義
米国FDA 物質登録 · UNII 68IQX3T69U · 登録名 PROPAFENONE · 単一の化学物質
Propafenone is an aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias. It has a role as an anti-arrhythmia drug. It is a secondary alcohol, a secondary amino compound and an aromatic ketone. It is a conjugate base of a propafenone(1+).
出典: PubChem
Propafenone is the organic compound that conforms to the formula
化粧品での役割
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
- CAS No.化学物質登録番号
- 54063-53-5
- DTXSID米国EPA化学物質番号
- DTXSID9045184
- DTXCID米国EPA化合物番号
- DTXCID7025184
- IUPAC
- 1-{2-[2-Hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one
- 分子式
- C21H27NO3
- 分子量
- 341.451 g/mol
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- SkinIrr2
Skin Irritation · QSAR Predicted
出典: 米国EPA CompTox
関連文献
- (N-NITROSO) PROPAFENONE INDUCED ADVANCED NODULAR MELANOMA-FIRST REPORTED CASE IN THE WORLD LITERATURE: THE INEXTRICABLE LINKS BETWEEN THE PHOTOCARCINOGENESIS, DRUG RELATED NITROSOGENESIS AND PHARMACO-ONCOGENESIS. · 2024
- Neutropenia and cutaneous lesions secondary to propafenone. · 2009
- POLYPHARMACY, DRUG RELATED NITROSAMINE CONTAMINATION (BISOPROLOL/PROPAFENONE) AND THE LINK TO LICHEN PLANUS/SUBSEQUENT DEVELOPMENT OF KERATINOCYTE AND MUCOSAL CANCER/ORAL LEUKOPLAKIA: PRESENTATION OF THE FIRST CASE AND UPDATE ON THE NEW PATHOGENETIC VISION. · 2025
- MULTIPLE KERATINOCYTIC CANCERS AFTER INTAKE OF ANTIHYPERTENSIVES (LISINOPRIL/BISOPROLOL/HCT) AND ANTIARRHYTMICS (PROPAFENONE): THE IMPORTANT NEW LINKS TO THE NITROSO-CONTAMINATION AND THE METABOLIC REPROGRAMMING OF THE FUTURE CANCER CELL. · 2024
- Atrial fibrillation: focal or reentrant or both?: a new autonomic lens to examine an old riddle. · 2009