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成分词典

成分词典

PROPAFENONE

Propafenone is an aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group.

分子结构

定义

美国FDA 物质登记 · UNII 68IQX3T69U · 登记名称 PROPAFENONE · 单一化学物质

来源: 美国FDA 物质识别码(UNII)

Propafenone is an aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias. It has a role as an anti-arrhythmia drug. It is a secondary alcohol, a secondary amino compound and an aromatic ketone. It is a conjugate base of a propafenone(1+).

来源: PubChem

Propafenone is the organic compound that conforms to the formula

化妆品中的作用

保护肌肤免受外界刺激SKIN PROTECTING
详细资料——标示名称、识别编号、物性、试验记录、文献

别名和识别信息

PROPAFENONEINCI프로파페논韩国标示名称(食药处标准名)
CAS No.化学物质登记号
54063-53-5
DTXSID美国EPA化学品编号
DTXSID9045184
DTXCID美国EPA化合物编号
DTXCID7025184
IUPAC
1-{2-[2-Hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one
分子式
C21H27NO3
分子量
341.451 g/mol

刺激与致敏试验记录

记录有皮肤试验 1 项、眼部试验 0 项。

归类为中等1 项

试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。

查看全部 1 项试验
  • SkinIrr2
    Skin Irritation · QSAR Predicted

来源: 美国EPA CompTox

相关文献

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