Ingredient Dictionary

PROPYL PROPIONATE

Propyl propionate is a propanoate ester resulting from the formal condensation of the hydroxy group of propanol with the carboxy group of propanoic acid.

Definition

Propyl propionate is a propanoate ester resulting from the formal condensation of the hydroxy group of propanol with the carboxy group of propanoic acid. It has a role as a biomarker, a fungal metabolite, a human metabolite and a rat metabolite. It is functionally related to a propan-1-ol.

Source: PubChem

US FDA substance register · UNII G09TRV00GK · registered name PROPYL PROPIONATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

PROPYL PROPIONATEINCIPropanoic acid, propyl esterSynonym

CAS No.chemical registry number: 106-36-5
EC No.EU chemical inventory number: 203-389-7
DTXSIDUS EPA chemical ID: DTXSID4042337
DTXCIDUS EPA compound ID: DTXCID2022337

IUPAC: Propyl propanoate
Molecular formula: C6H12O2
Molecular weight: 116.16 g/mol

Measured properties

Appearance: Liquid · colourless to pale yellow liquid with a fruity (apple, banana, pineapple) odour
Boiling point: 122.00 to 124.00 °C. @ 760.00 mm Hg · 122-124 °C
Melting point: -75.9 °C
Solubility: 5.3 mg/mL at 25 °C · miscible with alcohol, ether, propylene glycol, soluble 1 ml in 200 ml water
Density: 0.873-0.879
pH: 7
Melting/freezing point: -75 ℃
Initial boiling point and range: 122 ℃
Flash point: 58 ℃(EPA OPPTS 830.6315)
Vapour pressure: 13.9 ㎜Hg(25℃)
Water solubility: 5300 ㎎/ℓ(25℃)
n-Octanol/water partition coefficient (Kow): 1.85 (25℃)
Auto-ignition temperature: 356 ℃((1013hPa), EU Method A.15)
Viscosity: 0.7 mPa S(20℃)
Molecular weight: 116.16

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Solvent3
Fragrance3
Flavouring and nutrient2
Intermediate1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 1 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to