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Ingredient Dictionary

PROPYLENE CARBONATE

Propylene carbonate is an organic molecular entity.

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 712 list it before the 1% line and 425 after it (usually 1% or less).

Products using this ingredient

12 of 1,119 confirmed · likeliest to carry enough first · See all 1,119

Definition

Propylene carbonate is an organic molecular entity.

Source: PubChem

US FDA substance register · UNII 8D08K3S51E · registered name Propylene Carbonate · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Adjusts thicknessVISCOSITY CONTROLLINGBase that dissolves other ingredientsSOLVENT

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments - 2004/2005

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report: Amended Safety Assessment of Propylene Carbonate as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Propylene Carbonate

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name 炭酸プロピレン: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

PROPYLENE CARBONATEINCI프로필렌카보네이트Korean label name (MFDS standard)1,3-Dioxolan-2-one, 4-methyl-Synonym炭酸プロピレンJapanese labelling name
CAS No.chemical registry number
108-32-7
EC No.EU chemical inventory number
203-572-1
DTXSIDUS EPA chemical ID
DTXSID2026789
DTXCIDUS EPA compound ID
DTXCID006789
IUPAC
4-Methyl-1,3-dioxolan-2-one
Molecular formula
C4H6O3
Molecular weight
102.089 g/mol

Measured properties

Appearance
Liquid, Other Solid, CBI · Colorless odorless liquid, [Hawley] Somewhat hygroscopic, [CHEMINFO]
Odour
Odorless · Weak odor
Boiling point
241.6 °C · 242 °C @760 [mm Hg]
Melting point
-48.8 °C
Solubility
In water, 1.75X10+5 mg/L at 25 °C · Very soluble in ethanol, ether, acetone, benzene
Density
1.2047 g/cu cm at 20 °C · 1.2047 @ 20°C
Stability
Stable under recommended storage conditions.
Colour
colourless
Melting/freezing point
-48.8 ℃
Initial boiling point and range
242 ℃
Flash point
135 ℃(c.c.)
Flammability (solid, gas)
flammable
Upper/lower flammability or explosive limits
1.8 / 14.3 %
Vapour pressure
0.045 ㎜Hg (@ 25 ℃)
Water solubility
175000 ㎎/ℓ (@ 25 ℃)
Vapour density
3.52
Relative density
1.2047
n-Octanol/water partition coefficient (Kow)
-0.41
Auto-ignition temperature
430 ℃
Viscosity
2.76 cP (@ 20 ℃)
Molecular weight
102.09

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 153 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Viscosity modifier95
  • Thickening agent21
  • Solvent14
  • Processing aids not otherwise specified5
  • Solubility enhancer4
  • Conductive agent2
  • Monomers2
  • Chemical reaction regulator2
7 other uses
  • Lubricating agent2
  • Polymerization promoter1
  • Fragrance1
  • Cleaning agent1
  • Filler1
  • Catalyst1
  • Intermediate1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 6 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 9 studies
  • Classification not possible
    Skin Sensitization · Screening
  • Not classified
    Skin Irritation · Screening
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across
  • Category 2A
    Eye Irritation · Screening
  • Severe Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to EPA OPPTS 870.2400 (Acute Eye Irritation) according to
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
  • Eye Irrit. 2
    Eye Irritation · Authoritative
  • Serious eye damage/eye irritation - Category 2
    Eye Irritation · Screening

Source: US EPA CompTox dashboard

Related literature

Linked databases 20

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