Ingredient Dictionary

PROPYLENEDIAMINE

Propylenediamine is a diamine that is propane substituted by amino groups at positions 1 and 2.

Definition

Propylenediamine is a diamine that is propane substituted by amino groups at positions 1 and 2. Propylenediamine is commonly used as a bidentate ligand in the formation of coordination complexes. It has a role as a ligand.

Source: PubChem

US FDA substance register · UNII 2A4P522UGO · registered name 1,2-Propanediamine · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Propylenediamine is the organic compound that conforms to the formula:

Cosmetic roles

No declared roleNOT REPORTED

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

PROPYLENEDIAMINEINCI1,2-PropanediamineSynonym

CAS No.chemical registry number: 78-90-0
DTXSIDUS EPA chemical ID: DTXSID4021761
DTXCIDUS EPA compound ID: DTXCID701761

IUPAC: Propane-1,2-diamine
Molecular formula: C3H10N2
Molecular weight: 74.127 g/mol

Measured properties

Appearance: 1,2-propylenediamine appears as a colorless liquid with an ammonia-like odor. Strongly irritates skin and tissue. · Extremely hygroscopic liquid, [Merck Index] Colorless liquid with an ammoniacal odor, [CAMEO]
Boiling point: 248.9 °F at 760 mmHg (NTP, 1992) · 119 °C
Melting point: -35 °F (NTP, 1992) · -12 °C
Solubility: Very soluble (NTP, 1992) · Solubility in water: miscible
Density: 0.8584 (NTP, 1992) - Less dense than water, will float · Relative density (water = 1): 0.9
Colour: colourless
Melting/freezing point: -12 ℃
Initial boiling point and range: 119 ℃
Flash point: 33 ℃(c.c.)
Upper/lower flammability or explosive limits: 11.1 / 2.2 %
Vapour pressure: 1.2 ㎪ (20℃)
Water solubility: 100 g/100㎖ (25℃, est.)
Vapour density: 2.6
Relative density: 0.9
n-Octanol/water partition coefficient (Kow): -1.8
Auto-ignition temperature: 416 ℃
Molecular weight: 74.13

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Intermediate1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 1 eye studies are on record.

Classed as highly irritating1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 5 studies

Skin Corr. 1A
Skin Irritation · Authoritative
Category 8.2B (Category 1B)
Skin Irritation · Read Across
Category 1
Skin Irritation · Screening
Classification not possible
Skin Sensitization · Screening
Category 1
Eye Irritation · Screening