Definition
US FDA substance register · UNII D0LC3PH24P · registered name PROTODIOSCIN · single chemical substance
Protodioscin is a furostanol glycoside that consists of the trisaccharide alpha-L-Rha-(14)-[alpha-L-Rha-(12)]-beta-D-Glc attached to position 3 of 26-(beta-D-glucopyranosyloxy)-3beta,22-dihydroxyfurost-5-ene via a glycosidic linkage. Found in several plant species including yams, asparagus and funugreek. It has a role as an antineoplastic agent, an antilipemic drug, a neuroprotective agent, an anti-inflammatory agent, an apoptosis inducer and a plant metabolite. It is a beta-D-glucoside, a pentacyclic triterpenoid, a cyclic hemiketal, a steroid saponin and a trisaccharide derivative. It derives from a hydride of a furostan.
Source: PubChem
Protodioscin is the saponin isolated from the fruit of Tribulus terrestris and the seeds of Trigonella foenumgraecum
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 55056-80-9
- DTXSIDUS EPA chemical ID
- DTXSID901021361
- DTXCIDUS EPA compound ID
- DTXCID201506463
- IUPAC
- (17xi,22R,25R)-26-(beta-D-Glucopyranosyloxy)-22-hydroxyfurost-5-en-3beta-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside
- Molecular formula
- C51H84O22
- Molecular weight
- 1049.211 g/mol
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Related literature
- Saponins from Dioscorea nipponinca Makino rehabilitate UVB-induced skin photoaging by inhibiting oxidative stress and apoptosis via targeting STAT3. · 2025
- Photosensitization by Brachiaria ruziziensis in a sheep herd. · 2020
- Identification of lamb flocks susceptible and resistant against Brachiaria poisoning · 2016
- Fotossensibilização em ovinos associada à ingestão de Brachiaria brizantha no estado do Pará · 2010
- Hepatogenous photosensitization in goats associated with Brachiaria brizantha ingestion in Pará. · 2009