Definition
US FDA substance register · UNII 85H0HZU99M · registered name POVIDONE-IODINE · mixture
Cosmetic roles
Inhibits microbial growthANTIMICROBIAL
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction II/213 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
PVP-IODINEINCI2-Pyrrolidinone, 1-ethenyl-, homopolymer, compound with iodineSynonym
- CAS No.chemical registry number
- 25655-41-8
- DTXSIDUS EPA chemical ID
- DTXSID8035712
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Biocide2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 2 eye studies are on record.
Classed as moderate1
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Category 6.5B (Category 1)
Skin Sensitization · Read Across - Category 6.3A (Category 2)
Skin Irritation · Read Across - Skin corrosion/irritation - Category 2
Skin Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Serious eye damage/eye irritation - Category 2
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Contact dermatitis secondary to povidone‐iodine: A systematic review · 2024
- Respiratory Infections Early-Stage Medication: Inhalation Formulation & Dosage of PVP Iodine · 2021
- Inhalation Formulation & Dosage of PVP Iodine for Respiratory Infections Treatment · 2021
- Efficacy and tolerability of liposomal polyvinylpyrrolidone-iodine hydrogel for the localized treatment of chronic infective, inflammatory, dermatoses: an uncontrolled pilot study · 2017
- The use of PVP-iodine as an adjunct to non-surgical treatment of chronic periodontitis. · 2008
Linked databases 11
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- Tlooto literature search 2 3 4 5
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
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