Pyrroloquinoline quinone is a pyrroloquinoline having oxo groups at the 4- and 5-positions and carboxy groups at the 2-, 7- and 9-positions.
Definition
Pyrroloquinoline Quinone is the organic compound that conforms to the formula:
Pyrroloquinoline quinone is a pyrroloquinoline having oxo groups at the 4- and 5-positions and carboxy groups at the 2-, 7- and 9-positions. It has a role as an antioxidant, a cofactor, a water-soluble vitamin (role) and an anti-inflammatory agent. It is a member of orthoquinones, a pyrroloquinoline cofactor and a tricarboxylic acid. It is a conjugate acid of a pyrroloquinoline quinone(3-).
Source: PubChem
US FDA substance register · UNII 47819QGH5L · registered name PYRROLOQUINOLINEDIONE TRICARBOXYLIC ACID · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ピロロキノリンキノン: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 72909-34-3
- DTXSIDUS EPA chemical ID
- DTXSID3041162
- DTXCIDUS EPA compound ID
- DTXCID1021162
- IUPAC
- 4,5-Dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid
- Molecular formula
- C14H6N2O8
- Molecular weight
- 330.208 g/mol
Measured properties
- Appearance
- Solid
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Humectant2
- Antioxidant1
- Softener and conditioner1
Source: US EPA CompTox dashboard
Related literature
- Optimization of Culture Conditions for Pyrroloquinoline Quinone-Overproducing Mutant Hyphomicrobium denitrificans and Its Skin Bioactive Properties · 2026
- Effects of pyrroloquinoline quinone (PQQ) on skin wound healing in mice. · 2025
- The effects of pyrroloquinoline quinone disodium salt on brain function and physiological processes. · 2024
- Repression of the Antioxidant Pyrroloquinoline Quinone in Skin Aging Induced by Bmi-1 Deficiency · 2022
- Efficient Production of Lactobionic Acid Using Escherichia coli Capable of Synthesizing Pyrroloquinoline Quinone. · 2022
Linked databases 15
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
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