Pyruvic acid is a 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid.
How much products actually contain
8 products state the amountmedian 0.000055%
- under 0.01% 8
- 0.01–0.1% 0
- 0.1–1% 0
- 1% or more 0
Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.
Of the products containing it, 5 list it before the 1% line and 5 after it (usually 1% or less).
Products using this ingredient
10 of 10 confirmed · likeliest to carry enough first
ModeloAC Zero Solution0.005% stated
ESFOLIO3HA Clear Serum 50ml0.000055% stated
SOME BY MIAHA-BHA-PHA 30 Days Miracle Serum 50ml0.000053% stated
SOME BY MISOME BY MI AHA-BHA-PHA 30 Days Miracle Serum 50ml0.000053% stated
NaturiumNaturium The Smoother Glycolic Acid Exfoliating Body Wash
ESFOLIO3HA Clear All-In-One Soap 100g0.0005% stated
ESFOLIO3HA Clear Toner Pad 70 Sheets (145ml)0.000055% stated
ESFOLIO3HA Clear Cream 50g0.000055% stated
ESFOLIO3HA Clear Cream 250g0.000055% stated
TOSOWOONGCollagen Necktox Cream
Definition
Pyruvic acid is a 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis. It has a role as a cofactor and a fundamental metabolite. It is functionally related to a propionic acid. It is a conjugate acid of a pyruvate.
Source: PubChem
US FDA substance register · UNII 8558G7RUTR · registered name Pyruvic Acid · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ピルビン酸: 本品は、次の化学式で表される有機酸である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 127-17-3
- EC No.EU chemical inventory number
- 204-824-3
- DTXSIDUS EPA chemical ID
- DTXSID2021650
- DTXCIDUS EPA compound ID
- DTXCID801650
- IUPAC
- 2-Oxopropanoic acid
- Molecular formula
- C3H4O3
- Molecular weight
- 88.062 g/mol
Measured properties
- Appearance
- liquid
- Melting/freezing point
- 14 ℃
- Initial boiling point and range
- 165 ℃
- Flash point
- 54 ℃
- Upper/lower flammability or explosive limits
- 16.6 / 3.6 %
- Vapour pressure
- 1.29 ㎜Hg (at 25C)
- Vapour density
- 3.0
- Relative density
- 1.2
- n-Octanol/water partition coefficient (Kow)
- -1.24 (est.)
- Auto-ignition temperature
- 305 ℃
- Decomposition temperature
- 165 ℃
- Molecular weight
- 88.06
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance3
- Flavouring and nutrient2
- Deodorizer2
- No specific technical function1
- pH regulating agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Category 8.2C (Category 1C)
Skin Irritation · Read Across - Category 6.3A (Category 2)
Skin Irritation · Read Across - Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Screening of Candida glabrata Clinical Isolates for Pyruvic Acid Production Potentials · 2025
- From Liquid to Solid: Cocrystallization as an Engineering Tool for the Solidification of Pyruvic Acid · 2023
- A Split Face Comparative Study to Evaluate the Efficacy of 40% Pyruvic Acid vs. Microdermabrasion with 40% Pyruvic Acid on Biomechanical Skin Parameters in the Treatment of Acne Vulgaris · 2022
- Comparison the effectiveness of pyruvic acid 50% and salicylic acid 30% in the treatment of acne · 2016
- Clinical and Instrumental Evaluation of Skin Improvement after Treatment with a New 50% Pyruvic Acid Peel · 2006
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese