Gloshell
Ingredients

Ingredient Dictionary

QUATERNIUM-22

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 1 list it before the 1% line and 6 after it (usually 1% or less).

Products using this ingredient

7 of 7 confirmed · likeliest to carry enough first

Cosmetic roles

Leaves a thin film where appliedFILM FORMINGReduces staticANTISTATICSoftens hairHAIR CONDITIONING

Safety & regulatory references

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2007-2010

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Re-evaluation - Not Opened: Quaternium-22

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Quaternium-22

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name クオタニウム-22: 本品は、次の化学式で表される4級アンモニウム塩である。

Source: JCIA labelling names (Japan)

Names & identifiers

QUATERNIUM-22INCI쿼터늄-22Korean label name (MFDS standard)クオタニウム-22Japanese labelling name
CAS No.chemical registry number
51812-80-7
CAS No.chemical registry number
51812-80-7 / 82970-95-4
CAS No.chemical registry number
82970-95-4
EC No.EU chemical inventory number
257-440-3
DTXSIDUS EPA chemical ID
DTXSID601014646
DTXCIDUS EPA compound ID
DTXCID101437186
IUPAC
N-(2-Hydroxyethyl)-N,N-dimethyl-3-[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanamido]propan-1-aminium chloride (non-preferred name)
Molecular formula
C13H29ClN2O7
Molecular weight
360.83 g/mol

What products actually use it for

What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Anti-static agent3
  • Film former3
  • Softener and conditioner3

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 2 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 5 studies
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) Essentially similar to the Buehler test.
  • Ambiguous
    skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act not specified according to
  • Ambiguous
    skin irritation: in vivo · Screening · other guideline: US Federal Hazardous Substances Act according to
  • Ambiguous
    eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act, Section 191.12 according to
  • Ambiguous
    eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labeling Act Section 191.12 according to

Source: US EPA CompTox dashboard

Related literature

Linked databases 13